Table of Contents

1. Glial Modulators as Potential Treatments of Psychostimulant Abuse 2. The Vesicular Monoamine Transporter-2 (VMAT2): An Important Pharmacological Target for the Discovery of Novel Therapeutics to Treat Methamphetamine Abuse 3. Customizing Monoclonal Antibodies for the Treatment of Methamphetamine Abuse: Current and Future Applications 4. Monoamine Transporter Inhibitors and Substrates as Treatments for Stimulant Abuse 5. Bupropion and Bupropion Analogs as Treatments for CNS Disorders 6. The Role of Guanfacine as a Therapeutic Agent to Address Stress-related Pathophysiology in Cocaine Dependent Individuals 7. Beyond Small Molecule SAR – Using the Dopamine D3 Receptor Crystal Structure to Guide Drug Design 8. Dopamine D4 Receptors in Psychostimulant Addiction 9. Sigma Receptors as Potential Therapeutic Targets to Mitigate Psychostimulant Effects 10. Mixed Kappa/Mu Partial Opioid Agonists as Potential Treatments for Cocaine Dependence 11. The Combination of Metyrapone and Oxazepam for the Treatment of Cocaine and Other Drug Addictions 12. Salvinorin A Analogs and Other Kappa Opioid Receptor Compounds as Treatments for Cocaine Abuse 13. Nicotinic Receptor Antagonists as Treatments for Nicotine Abuse 14. New Directions in Nicotine Vaccine Design and Use 15. Bath Salts, Mephedrone, and Methylenedioxypyrovalerone as Emerging Illicit Drugs That Will Need Targeted Therapeutic Intervention