Oxytocin: Methods and Protocols

Oxytocin: Methods and Protocols

Oxytocin: Methods and Protocols

Oxytocin: Methods and Protocols

Hardcover(1st ed. 2022)

$199.99 
  • SHIP THIS ITEM
    Qualifies for Free Shipping
  • PICK UP IN STORE
    Check Availability at Nearby Stores

Related collections and offers


Overview

This detailed book explores techniques for further elucidating the peripheral and central roles of oxyin as well as techniques key to oxyin receptor-related drug discovery. The first set of chapters explore this neuropeptide’s peripheral and central effects, such as regulation of myometrial contraction, induction of cardioprotective effects, and the facilitation of pro-social behaviors. The book then continues by delving into a comprehensive pharmacological characterization of oxyin receptor ligands and ligands of other key receptors such as the vasopressin receptor family. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory prools, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Oxyin: Methods and Prools is an ideal guide for researchers seeking to further our knowledge of the varied and power effects of oxyin within the central nervous system.

Product Details

ISBN-13: 9781071617588
Publisher: Springer US
Publication date: 09/23/2021
Series: Methods in Molecular Biology , #2384
Edition description: 1st ed. 2022
Pages: 272
Product dimensions: 7.01(w) x 10.00(h) x (d)

Table of Contents

The Importance of Experimental Investigation of the Peripheral Oxyin System.- Human Myometrial Contractility Assays.- The Effect of Oxyin on Intracellular Ca2+ Release in Cardiac Cells.- The Importance of Experimental Investigation of the CNS Oxyin System.- The Role of Oxyin in Social Circuits and Social Behavior in Dementia.- Evaluating Methylation of the Oxyin Receptor Gene and the Oxyin Intergenic Region.- Using Receptor Autoradiography to Visualize and Quantify Oxyin and Vasopressin 1a Receptors in the Human and Nonhuman Primate Brain.- Linking Central Gene Expression Patterns and Mental States Using Transcriptomics and Large-Scale Meta-Analysis of fMRI Data: A Tutorial and Example Using the Oxyin Signaling Pathway.- CRISPR/Cas9-Mediated Genetic Engineering to Generate a Disease Model Prairie Vole, Based on the Species-Optimized Assisted Reproductive Technology.- The Current Status of Drug Discovery for the Oxyin Receptor.- Fmoc Solid PhasePeptide Synthesis of Oxyin and Analogues.- Employing the Operational Model to Measure System-Independent OTR Efficacy.- Use of BRET to Measure β-Arrestin Recruitment at Oxyin and Vasopressin Receptors.- Measuring Affinity of Ligands to the Oxyin Receptor Using Radioligand Binding.- Use of Co-Cultures to Measure the Blood-Brain Barrier Permeability of Oxyin.- Intracerebral Delivery of an OTR Antagonist and Subsequent Behavioral Testing in Prairie Voles.

From the B&N Reads Blog

Customer Reviews