Table of Contents

Section I: Clinical Aspects of CAA and CAA-Related Hemorrhage.- 1 Clinical aspects and diagnostic criteria of sporadic CAA-related hemorrhage.- 2 Diagnosis of CAA during life. Neuroimaging of CAA.- 3 Vascular risk factors for Alzheimer’s disease. An epidemiologic perspective.- 4 Cerebral microvascular and macrovascular disease in the aging brain; similarities and differences.- Section II: Genetics of CAA.- 5 ApoE genotype in relation to sporadic and Alzheimer-related CAA.- 6 Clinical and genetic aspects of hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D).- 7 Genetics and neuropathology of hereditary cystatin C amyloid angiopathy (HCCAA).- Section III: Cellular and Molecular Pathology of CAA.- 8 Neuropathologic features and grading of Alzheimer-related and sporadic CAA.- 9 Chemical analysis of amyloid ? protein in CAA.- 10 Immunohistochemical analysis of amyloid ? protein isoforms in CAA.- 11 Blood Brain Barrier dysfunction and cerebrovascular degeneration in Alzheimer’s disease.- 12 A?-associated proteins in cerebral amyloid angiopathy.- 13 Neuropathology of hereditary cerebral hemorrhage with amyloidosis-Dutch type.- 14 Neuropathology and genetics of prion protein and British cerebral amyloid angiopathies.- Section IV: In Vitro and Animal Models of CAA.- 15 Amyloid ? protein internalization and production by canine smooth muscle cells.- 16 Degeneration of human cerebrovascular smooth muscle cells and pericytes caused by amyloid ? protein.- 17 Vasoactivity of amyloid ? peptides.- 18 CAA in transgenic mouse models of Alzheimer’s disease. What can we learn from APP transgenic mouse models?.- 19 Cerebral amyloid angiopathy in aged dogs and nonhuman primates.- 20 Vascular transport of Alzheimer’s amyloid ? peptides and apolipoproteins.