Male infertility may occur due to different causes, therefore, different therapeutic approaches have been applied in order to improve the ability of men to get children.Two hundred and fifty infertile men were treated with Royal Jelly, from them twenty-two infertile men with 100&50 and 25 mg/day of Royal Jelly.After three months of treatment, the active sperm motility, testosterone level, LH level, sluggishly motile sperm and intercourse/week were increased significantly in infertile men treated with Royal Jelly, while sperm count and FSH level were insignificant.