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Precision Radiation Oncology

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Precision Radiation Oncology

eBook

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eBook
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Overview

Precision medicine is a rapidly-evolving field in the management of cancer. The use of novel molecular or genetic signatures in local-regional management is still in its infancy. Precision Radiation Oncology demystifies this state-of-the-art research and technology.

By describing current existing clinical and pathologic features, and focusing on the ability to improve outcomes in cancer using radiation therapy, this book discusses incorporating novel genomic- or biology-based biomarkers in the treatment of patients moving radiation oncology into precision/personalized medicine. Precision Radiation Oncology provides readers with an overview of the new developments of precision medicine in radiation oncology, further advancing the integration of new research findings into individualized radiation therapy and its clinical applications.

Product Details

ISBN-13:	9780813592541
Publisher:	Rutgers University Press
Publication date:	05/24/2018
Series:	Current Precision Oncology
Sold by:	Barnes & Noble
Format:	eBook
Pages:	328
File size:	18 MB
Note:	This product may take a few minutes to download.

About the Author

BRUCE HAFFTY, M.D. is an international expert in breast radiation oncology. He is a professor and chairman in the Department of Radiation Oncology at Rutgers Robert Wood Johnson Medical School, Rutgers New Jersey Medical School, and Rutgers Cancer Institute of New Jersey. He also serves as Chief of Staff of the Rutgers Cancer Institute.

SHARAD GOYAL, M.D. is a professor and division chief of Radiation Oncology in the Department of Radiology at the George Washington University School of Medicine and Health Sciences. He is a board-certified radiation oncologist whose clinical practice is primarily focused on breast and brain cancers.

Contributors

Precision Radiation Oncology: An Introduction by Sharad Goyal, Sachin Jhawar, and Bruce G. Haffty
1. Combining Cytotoxic Chemotherapy and Radiation Therapy by Vivek Verma and Charles B. Simone II
2. Molecular Targeted Therapy and Radiation by Stephen A. Rosenberg, Zachary S. Morris, and Randall J. Kimple
3. Current State of the Art in Intracranial Stereotactic Radiosurgery Technology: Accuracy, Precision, and Clinical Impact by George Farha, David Schlesinger, Arman Sarfehina, Argun Sahgal, and Mark Ruschin
4. Spine Radiosurgery in the Management of Spine Metastasis by Neil K. Taunk and Sharad Goyal
5. Body Radiosurgery by Jordan A. Torok, Manisha Palta, and Joseph K. Salama
6. Brachytherapy by Dodul Mondal, Omar Mahmoud, and Atif J. Khan
7. Proton Beam Therapy by Ryan Rhome and Rahul R. Parikh
8. Intraoperative Radiation Therapy by Daniel J. Tandberg, Christopher G. Willett, Manisha Palta, and Brian G. Czito
9. Nanomedicines: Diagnostic and Therapeutic Applications in Radiation Oncology by Joseph M. Caster, Tian Zhang, Artish N. Patel, Nichole J. Newman, and Andrew Z. Wang
10. Radiolabeled Spheres by John Byun, John L. Nosher, and Salma K. Jabbour
11. Radiogenomics: Advancing Precision Radiation Oncology Through Development of a Genomic-Based Predictive Instrument by Barry S. Rosenstein
12. Combined Effects of Immunotherapy and Radiation Therapy by Sachin Jhawar and Ann W. Silk
13. Radiomics by Ke Nie and Min-Ying Lydia Su
14. Big Data and Radiation Oncology by Sanjay Aneja and James B. Yu

Index

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Editorial Reviews

Reviewer: Mark D. Hurwitz, MD (Thomas Jefferson University)
Description: The authors of this book take a broad approach in addressing the topic of precision in radiation oncology, ranging from well-written reviews of target therapies, such as brachytherapy and stereotactic radiosurgery, to more novel areas such as radiomics and big data.
Purpose: The purpose is to present diverse strategies for achieving precise delivery of radiation oncology. Here precision is defined as the ability to maximize the anti-tumor effect while avoiding unnecessary toxicity, without jeopardizing the patient's outcome. This is a worthy objective, and the book takes a broad yet nuanced approach to address it.
Audience: Practicing radiation oncologists may find this book of particular interest as it provides a relatively succinct but well-done review of several standard and emerging therapies in the field, as well as additional topics such as radiomics or big data with which they may be less familiar. Residents and medical students also may find the book of interest. Lastly, radiobiologists and medical physicists will find at least some of the topics of interest. While there are a number of trainees and junior faculty who have authored chapters, in most cases they are paired with well-established senior authors. Regardless of experience, the authors have, in general, written high quality chapters.
Features: The 14 chapters cover a range of diverse topics, including state-of-the art clinical treatment strategies and modalities, emerging therapeutics, and bridges between radiology and computer science with radiation oncology. Because of its relatively succinct nature that makes it easy to read, this book does not fully cover some emerging fields and topics. Those seeking in-depth understanding of these topics will find it necessary in many instances to seek more comprehensive literature on a given subject.
Assessment: I enjoyed reading a number of chapters on topics that to date have been peripheral to the practice of radiation oncology, but now increasingly are converging with this specialty. In addition, the chapters covering more of the "bread and butter" topics in the field are well written, striking a nice balance in their review of often very large topics. The book by its nature is not a "go-to" tome and therefore not an essential addition to one's library, but it is an informative and well thought out effort that addresses precision in radiation oncology.

Doody's Review Service

Precision Radiation Oncology

Precision Radiation Oncology

eBook

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Overview

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About the Author

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