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A Handbook of Neurological Investigations in Children

Neurological disorders in children are common: families want to know what is wrong, why it happened, and whether it will happen again. Management and treatment depend on establishing the diagnosis, which usually requires investigations, but the number of possible neurological investigations is now very large indeed, and uncritical investigations may be seriously misleading and often costly. This book, based on the authors’ vast combined personal experience, gives practical guidance on how to target any specific condition with the minimum of tests. Part 1 is a brief distillation of advice on clinical history and examination, introducing the problems that beset those who deal with neurological disorders in childhood. Part 2 outlines the investigations available to solve these diagnostic problems. Part 3 takes a problem-oriented approach to the most appropriate investigations in the various clinical scenarios that may present to the practitioner: the starting point is the patient’s presentation, not the diagnosis. Throughout, vignettes of real cases help to illustrate the use of the tests in different clinical situations. The authors co-wrote the hugely popular Handbook of Neurological Investigations (“the Blue Book”) 20 years ago. This new book, while closely following the highly successful approach of the earlier title, is thoroughly up to date, with fresh material, new case vignettes, and additional investigations covered.

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A Handbook of Neurological Investigations in Children

Neurological disorders in children are common: families want to know what is wrong, why it happened, and whether it will happen again. Management and treatment depend on establishing the diagnosis, which usually requires investigations, but the number of possible neurological investigations is now very large indeed, and uncritical investigations may be seriously misleading and often costly. This book, based on the authors’ vast combined personal experience, gives practical guidance on how to target any specific condition with the minimum of tests. Part 1 is a brief distillation of advice on clinical history and examination, introducing the problems that beset those who deal with neurological disorders in childhood. Part 2 outlines the investigations available to solve these diagnostic problems. Part 3 takes a problem-oriented approach to the most appropriate investigations in the various clinical scenarios that may present to the practitioner: the starting point is the patient’s presentation, not the diagnosis. Throughout, vignettes of real cases help to illustrate the use of the tests in different clinical situations. The authors co-wrote the hugely popular Handbook of Neurological Investigations (“the Blue Book”) 20 years ago. This new book, while closely following the highly successful approach of the earlier title, is thoroughly up to date, with fresh material, new case vignettes, and additional investigations covered.

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A Handbook of Neurological Investigations in Children

A Handbook of Neurological Investigations in Children

A Handbook of Neurological Investigations in Children
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A Handbook of Neurological Investigations in Children

A Handbook of Neurological Investigations in Children

Overview

Neurological disorders in children are common: families want to know what is wrong, why it happened, and whether it will happen again. Management and treatment depend on establishing the diagnosis, which usually requires investigations, but the number of possible neurological investigations is now very large indeed, and uncritical investigations may be seriously misleading and often costly. This book, based on the authors’ vast combined personal experience, gives practical guidance on how to target any specific condition with the minimum of tests. Part 1 is a brief distillation of advice on clinical history and examination, introducing the problems that beset those who deal with neurological disorders in childhood. Part 2 outlines the investigations available to solve these diagnostic problems. Part 3 takes a problem-oriented approach to the most appropriate investigations in the various clinical scenarios that may present to the practitioner: the starting point is the patient’s presentation, not the diagnosis. Throughout, vignettes of real cases help to illustrate the use of the tests in different clinical situations. The authors co-wrote the hugely popular Handbook of Neurological Investigations (“the Blue Book”) 20 years ago. This new book, while closely following the highly successful approach of the earlier title, is thoroughly up to date, with fresh material, new case vignettes, and additional investigations covered.

Product Details

ISBN-13: 9781907655548
Publisher: MacKeith Press
Publication date: 01/01/2010
Series: 4
Sold by: Barnes & Noble
Format: eBook
Pages: 404
File size: 47 MB
Note: This product may take a few minutes to download.

About the Author

Consultant Paediatric Neurologist, Children’s University Hospital, Dublin, Ireland
Honorary Professor in Paediatric Neurology and Senior Research Fellow, Division of Developmental Medicine, University of Glasgow, UK

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Contents

Authors viii

Acknowledgements ix

Foreword xi

Rob Rust

Abbreviations xiii

Introduction 1

Part 1

1.1 History Highlights 7

1.2 Examination Essentials 11

Part 2. Investigations

2.1 Video with Audio 14

2.2 Electroencephalography 22

2.3 Electromyography and Nerve Conduction Studies 40

2.4 Evoked Potentials 49

2.5 Structural Imaging 55

Contents

2.6 Functional Imaging 85

2.7 Cerebrospinal Fluid 93

2.8 Cardiac Tests and Autonomic Function 105

2.9 Microscopic Examinations: Cells and Biopsies 112

2.10 Microbiology 123

2.11 Haematology 129

2.12 Immunology 134

2.13 Genetic Investigations 144

2.14 Biochemistry 151

2.15 Antiepileptic Drug Monitoring 198

2.16 Diagnosis by Clinical Trial 201

Part 3. Clinical Settings

3.1 Neonatal Seizures 208

3.2 Abnormal Neonatal Neurology 214

3.3 Delayed Development 223

3.4 Floppy Infant 228

3.5 Abnormal Head Size 235

3.6 Wobbly-eyed Baby 240

3.7 ‘Cerebral Palsy’ 243

3.8 Peculiar Gait 251

3.9 Learning Disability/Mental Retardation 259

3.10 Speech and Language Disorders 265

3.11 ‘Psychiatric’ Disorders 271

3.12 Epileptic Seizures and Epilepsy 275

3.13 Febrile Seizures 294

3.14 Paroxysmal Non-epileptic Disorders 297

3.15 Epileptic and Non-epileptic Disorders Together 305

3.16 Acquired Neurological Deficits 310

3.17 Acute Encephalopathy 318

3.18 Headache 327

3.19 Weakness and Fatigue 330

3.20 Ataxia 333

3.21 Movement Disorders 337

3.22 Progressive Loss of Skills and Dementia 344

3.23 Rare Treatable Disorders 355

Appendix 1. Predictive Value of Investigation Results 364

Appendix 2. Some Normal Values 368

Appendix 3. List of Clinical Vignettes 371

Index 373

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