Life from an RNA World: The Ancestor Within

Life from an RNA World: The Ancestor Within

by Michael Yarus
Life from an RNA World: The Ancestor Within

Life from an RNA World: The Ancestor Within

by Michael Yarus

Paperback

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Overview

A majority of evolutionary biologists believe that we now can envision our biological predecessors—not the first, but nearly the first, living beings on Earth. Life from an RNA World is about these vanished forebears, sketching them in the distant past just as their workings first began to resemble our own. The advances that have made such a pursuit possible are rarely discussed outside of bio-labs. So here, says author Michael Yarus, is an album for interested non-biologists, an introduction to our relatives in deep time, slouching between the first rudimentary life on Earth and the appearance of more complex beings.

The era between, and the focus of Yarus’ work, is called the RNA world. It is RNA (ribonucleic acid)—long believed to be a mere biologic copier and messenger—that offers us this glimpse into our ancient predecessors. To describe early RNA creatures, here called “ribocytes” or RNA cells, Yarus deploys some basics of molecular biology. He reviews our current understanding of the tree of life, examines the structure of RNA itself, explains the operation of the genetic code, and covers much else—all in an effort to reveal a departed biological world across billions of years between its heyday and ours.

Courting controversy among those who question the role of “ribocytes”—citing the chemical fragility of RNA and the uncertainty about the origin of an RNA synthetic apparatus—Yarus offers an invaluable vision of early life on Earth. And his book makes that early form of life, our ancestor within, accessible to all of us.


Product Details

ISBN-13: 9780674060715
Publisher: Harvard University Press
Publication date: 03/18/2011
Pages: 208
Product dimensions: 8.04(w) x 5.52(h) x 0.50(d)

About the Author

Michael Yarus is Professor Emeritus, Department of Molecular, Cellular, and Developmental Biology, University of Colorado.

Table of Contents

  • Introduction to Your Ancestor

  1. Before We Begin: A Voluntary Chapter
  2. Framing the Problem: The Buffalo and the Bacterium
  3. The Big Tree: No Jackalopes Please
  4. A Dance of Atoms
  5. Allegro Agitato: The Origin of Life
  6. The Winds That Blow through the Starry Ways
  7. Tornados in a Junkyard
  8. Between Genomes and Creatures
  9. A Thumbnail Molecular Biology
  10. RNA Structure: A Tape with a Shape
  11. Intimations of an RNA World
  12. The Experimentally Impaired Sciences
  13. Test Tube RNA Evolution: First Light
  14. Selection Amplification: Interrogating RNA’s Possibilities
  15. RNA Duplication: Replicase Activity in Real RNAs
  16. RNA Capabilities and the Origins of Translation
  17. The Quest for the Peptidyl Transferase
  18. A Language Much Older Than Hieroglyphics: The Genetic Code
  19. Assume a Spherical Cow: The Ribocyte
  20. The Future of the RNA World

  • Lexicon
  • Index

What People are Saying About This

Thomas Cech

Yarus captivates with skilled character development -- but here, the “characters” are the prebiotic molecules that gave rise to everything that has ever lived or is alive today on our planet.

Thomas Cech, Distinguished Professor, University of Colorado-Boulder, Nobel Laureate in Chemistry, 1989

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