Harper's Illustrated Biochemistry, Thirty-Second Edition
A Doody's Core Title for 2023!

Gain a thorough understanding of the principles of biochemistry as they relate to clinical medicine

The Thirty-Second Edition of Harper's Illustrated Biochemistry combines top-quality full-color illustrations with authoritative integrated coverage of biochemical disease and clinical information. Featuring numerous medically relevant examples, this respected text presents a clear, succinct review of the fundamentals that every student must understand in order to succeed in medical school.

All 58 chapters help you understand the medical relevance of biochemistry.

  • Full-color presentation with 600+ illustrations
  • Chapters have been updated to reflect the latest information
  • Case studies emphasize the clinical relevance of biochemistry
  • Review questions follow each of the 11 sections
  • Boxed objectives define the goals of each chapter
  • Tables encapsulate important information
  • Each chapter contains a section on biomedical importance and a summary of the topics covered

Applauded by medical students for its current and engaging style, Harper’s Illustrated Biochemistry is an essential for USMLE review and the single best reference for learning the clinical relevance of any biochemistry topic.

1145487424
Harper's Illustrated Biochemistry, Thirty-Second Edition
A Doody's Core Title for 2023!

Gain a thorough understanding of the principles of biochemistry as they relate to clinical medicine

The Thirty-Second Edition of Harper's Illustrated Biochemistry combines top-quality full-color illustrations with authoritative integrated coverage of biochemical disease and clinical information. Featuring numerous medically relevant examples, this respected text presents a clear, succinct review of the fundamentals that every student must understand in order to succeed in medical school.

All 58 chapters help you understand the medical relevance of biochemistry.

  • Full-color presentation with 600+ illustrations
  • Chapters have been updated to reflect the latest information
  • Case studies emphasize the clinical relevance of biochemistry
  • Review questions follow each of the 11 sections
  • Boxed objectives define the goals of each chapter
  • Tables encapsulate important information
  • Each chapter contains a section on biomedical importance and a summary of the topics covered

Applauded by medical students for its current and engaging style, Harper’s Illustrated Biochemistry is an essential for USMLE review and the single best reference for learning the clinical relevance of any biochemistry topic.

108.0 In Stock
Harper's Illustrated Biochemistry, Thirty-Second Edition

Harper's Illustrated Biochemistry, Thirty-Second Edition

Harper's Illustrated Biochemistry, Thirty-Second Edition

Harper's Illustrated Biochemistry, Thirty-Second Edition

Paperback(32nd ed.)

$108.00 
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Overview

A Doody's Core Title for 2023!

Gain a thorough understanding of the principles of biochemistry as they relate to clinical medicine

The Thirty-Second Edition of Harper's Illustrated Biochemistry combines top-quality full-color illustrations with authoritative integrated coverage of biochemical disease and clinical information. Featuring numerous medically relevant examples, this respected text presents a clear, succinct review of the fundamentals that every student must understand in order to succeed in medical school.

All 58 chapters help you understand the medical relevance of biochemistry.

  • Full-color presentation with 600+ illustrations
  • Chapters have been updated to reflect the latest information
  • Case studies emphasize the clinical relevance of biochemistry
  • Review questions follow each of the 11 sections
  • Boxed objectives define the goals of each chapter
  • Tables encapsulate important information
  • Each chapter contains a section on biomedical importance and a summary of the topics covered

Applauded by medical students for its current and engaging style, Harper’s Illustrated Biochemistry is an essential for USMLE review and the single best reference for learning the clinical relevance of any biochemistry topic.


Product Details

ISBN-13: 9781260469943
Publisher: McGraw Hill LLC
Publication date: 09/07/2022
Edition description: 32nd ed.
Pages: 816
Sales rank: 845,178
Product dimensions: 8.60(w) x 10.80(h) x 1.40(d)

About the Author

Robert K. Murray, MD, PhD
Professor (Emeritus) of Biochemistry
University of Toronto
Toronto, Ontario

Daryl K. Granner, MD
Joe C. Davis Professor of Biomedical Science
Director, Vanderbilt Diabetes Center
Professor of Molecular Physiology and Biophysics and of Medicine
Vanderbilt University
Nashville, Tennessee

Peter A. Mayes, PhD, DSc
Emeritus Professor of Veterinary Biochemistry
Royal Veterinary College
University of London
London

Victor W. Rodwell, PhD
Professor of Biochemistry
Purdue University
West Lafayette, Indiana

Peter Kennelly, Ph.D., is professor and head of the Department of Biochemistry at Virginia Polytechnic Institute and State University in Blacksburg, Virginia.

Owen McGuinness, Ph.D., is a professor in the Department of Molecular Physiology and Biophysics at Vanderbilt University in Nashville, Tennessee.

Kathleen M. Botham, PhD, DSc, is professor (emeritus) of Biochemistry in the Department of Comparative Biomedical Sciences at Royal Veterinary College, University of London in the United Kingdom.

Victor W. Rodwell, PhD, is a professor (emeritus) of Biochemistry at Purdue University in West Lafayette, Indiana.

P. Anthony Weil, PhD, is a professor in the Department of Molecular Physiology & Biophysics at Vanderbilt University in Nashville, Tennessee.






Table of Contents

Preface ix

Section I Structures & Functions of Proteins & Enzymes 1

1 Biochemistry & Medicine Victor W. Rodweli, PhD 1

2 Water & pH Peter J. Kennelly, PhD Victor W. Rodweli, PhD 6

3 Amino Acids & Peptides Peter J. Kennelly, PhD Victor W. Rodweli, PhD 15

4 Proteins: Determination of Primary Structure Peter J. Kennelly, PhD Victor W. Rodweli, PhD 24

5 Proteins: Higher Orders of Structure Peter J. Kennelly, PhD Victor W. Rodweli, PhD 34

Section II Enzymes: Kinetics, Mechanism, Regulation, & Role of Transition Metals 49

6 Proteins: Myoglobin & Hemoglobin Peter J. Kennelly, PhD Victor W. Rodwell, PhD 49

7 Enzymes: Mechanism of Action Peter J. Kennelly, PhD Victor W. Rodweli, PhD 59

8 Enzymes: Kinetics Victor W. Rodweli, PhD 71

9 Enzymes: Regulation of Activities Peter J. Kennelly, PhD Victor W. Rodweli, PhD 85

10 The Biochemical Roles of Transition Metals Peter J. Kennelly, PhD 96

Section III Bioenergetics 109

11 Bioenergetics: The Role of ATP Kathleen M. Botham, PhD, DSc Peter A. Mayes, PhD, DSc 109

12 Biologic Oxidation Kathleen M. Botham, PhD, DSc Peter A. Mayes, PhD, DSc 115

13 The Respiratory Chain & Oxidative Phosphorylation Kathleen M. Botham, PhD, DSc Peter A. Mayes, PhD, DSc 121

Section IV Metabolism of Carbohydrates 133

14 Overview of Metabolism & the Provision of Metabolic Fuels Owen P. McGuinness, PhD 133

15 Saccharides (ie. Carbohydrates) of Physiological Significance Owen P. McGuinness, PhD 147

16 The Citric Acid Cycle: A Pathway Central to Carbohydrate, Lipid, & Amino Acid Metabolism Owen P. McGuinness, PhD 156

17 Glycolysis & the Oxidation of Pyruvate Owen P. McGuinness, PhD 163

18 Metabolism of Glycogen Owen P. McGuinness, PhD 171

19 Gluconeogenesis & the Control of Blood Glucose Owen P. McGuinness, PhD 180

20 The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism Owen P. McGuinness, PhD 191

Section V Metabolism of Lipids 205

21 Lipids of Physiologic Significance Kathleen M. Botham, PhD, DSc Peter A. Mayes, PhD, DSc 205

22 Oxidation of Fatty Acids: Ketogenesis Kathleen M. Botham, PhD, DSc Peter A. Mayes, PhD, DSc 217

23 Biosynthesis of Fatty Acids & Eicosanoids Kathleen M. Botham, PhD, DSc Peter A. Mayes, PhD, DSc 226

24 Metabolism of Acylglycerols & Sphingolipids Kathleen M. Botham, PhD, DSc Peter A. Mayes, PhD, DSc 239

25 Lipid Transports Storage Kathleen M. Botham, PhD, DSc Peter A. Mayes, PhD, DSc 247

26 Cholesterol Synthesis, Transport, & Excretion Kathleen M. Botham, PhD, DSc Peter A. Mayes, PhD, DSc 259

Section VI Metabolism of Proteins & Amino Acids 273

27 Biosynthesis of the Nutritionally Nonessential Amino Acids Victor W. Rodwell, PhD 273

28 Catabolism of Proteins & of Amino Acid Nitrogen Victor W. Rodwell, PhD 279

29 Catabolism of the Carbon Skeletons of Amino Acids Victor W. Rodwell, PhD 290

30 Conversion of Amino Acids to Specialized Products Victor W. Rodwell, PhD 306

31 Porphyrins & Bile Pigments Victor W. Rodwell, PhD 315

Section VII Structure, Function, & Replication of Informational Macromolecules 329

32 Nucleotides Victor W. Rodwell, PhD 329

33 Metabolism of Purine & Pyrimidine Nucleotides Victor W. Rodwell, PhD 337

34 Nucleic Acid Structures Function P. Anthony Weil, PhD 348

35 DNA Organization, Replication, & Repair P. Anthony Weil, PhD 360

36 RNA Synthesis, Processing, & Modification P. Anthony Weil, PhD 384

37 Protein Synthesis & the Genetic Code P. Anthony Weil, PhD 404

38 Regulation of Gene Expression P. Anthony Weil, PhD 420

39 Molecular Genetics, Recombinant DNA, & Genomic Technology P. Anthony Weil, PhD 444

Section VIII Biochemistry of Extracellular & Intracellular Communication 467

40 Membranes: Structure & Function P. Anthony Weil, PhD 467

41 The Diversity of the Endocrine System P. Anthony Weil, PhD 488

42 Hormone Action & Signal Transduction P. Anthony Weil, PhD 508

Section IX Special Topics (A) 527

43 Nutrition, Digestion, & Absorption David A. Bender, PhD 527

44 Micronutrients: Vitamins & Minerals David A. Bender, PhD 535

45 Free Radicals & Antioxidant Nutrients David A. Bender, PhD 549

46 Glycoproteins David A. Bender, PhD 554

47 Metabolism of Xenobiotics David A. Bender, PhD Robert K. Murray, MD, PhD 564

48 Clinical Biochemistry David A. Bender, PhD 568

Section X Special Topics (B) 581

49 Intracellular Traffic & Sorting of Proteins Kathleen M. Botham, PhD, DSc Robert K. Murray, MD, PhD 581

50 The Extracellular Matrix Kathleen M. Botham, PhD, DSc Robert K. Murray, MD, PhD 599

51 Muscle & the Cytoskeleton January D. Haile, PhD Peter J. Kennelly, PhD 618

52 Plasma Proteins & Immunoglobulins Peter J. Kennelly, PhD 634

53 Red Blood Cells Peter J. Kennelly, PhD 653

54 White Blood Cells Peter J. Kennelly, PhD 664

Section XI Special Topics (C) 677

55 Hemostasis&Thrombosis Peter L. Gross, MD, MSc, FRCP(C) P. Anthony Weil, PhD Margaret L. Rand, PhD 677

56 Cancer: An Overview Molly Jacob, MD, PhD, MNASc, FRCPath Joe Varghese, MD, PhD P. Anthony Weil, PhD 689

57 The Biochemistry of Aging Peter J. Kennelly, PhD 717

58 Biochemical Case Histories David A. Bender, PhD 729

The Answer Bank 741

Index 745

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