Andy Warhol was born in Pittsburgh, Pennsylvania on August 6, 1928.

He was the fourth child of Andrij Warhola (died 1942) and Julia (née Zavacka, 1892–1972), whose first child was born in their homeland and died before their move to the U.S. His parents were working-class Rusyns (or Lemkos) emigrants from Mikó (now called Miková), located in today’s northeastern Slovakia, part of the former Austro-Hungarian Empire.

Warhol's father immigrated to the US in 1914, and his mother joined him in 1921, after the death of Warhol's grandparents. Warhol's father worked in a coal mine. The family lived at 55 Beelen Street and later at 3252 Dawson Street in the Oakland neighborhood of Pittsburgh.

The family was Byzantine Catholic and attended St. John Chrysostom Byzantine Catholic Church. Andy Warhol had two older brothers - Pavol (Paul), the oldest, was born in Slovakia; Ján was born in Pittsburgh. Pavol's son, James Warhola, became a successful children's book illustrator.