Prelude
Jerrold Meinwald

The Search for Habitable Worlds: Planetary Exploration in the 21st Century
James F. Bell III

E pluribus unum: From Complexity, Universality
Terence Tao

Small Machines
Paul L. McEuen

Can We Progress from Solipsistic Science to Frugal Innovation?
Daniel G. Nocera

The Future of Fundamental Physics
Nima Arkani-Hamed

Microbes as Menaces, Mates & Marvels
Bonnie L. Bassler

Fossils Everywhere
Neil H. Shubin

Deciphering the Parts List for the Mechanical Plant
Chris Somerville

The Coming Epidemic of Neurologic Disorders: What Science Is – and Should Be – Doing About It
Gregory A. Petsko

Biodiversity & Environmental Sustainability amid Human Domination of Global Ecosystems
David Tilman

Postlude
May R. Berenbaum