Table of Contents

Foreword; B. Swynghedauw. Preface; P. Cummins. Introduction. 1. Growth factors: in vivo function and mechanism of action; C.-H. Heldin, L. Claesson-Welsh, K. Miyazono, B. Westermark. Section one: Growth Factors in the Heart. 2. Fibroblast and transforming growth factors in the heart: a role for cardiac growth? P. Cummins, A.K. El Amrani, F. El Amrani. 3. Growth factors and the cardiac extra-cellular matrix; L. Rappaport, J.L. Samuel. Section two: Growth Factors and the Cardiac Myocyte. 4. Transforming growth factor beta: Localisation and possible functional roles in cardiac myocytes; A.B. Roberts, M.B. Sporn. 5. Basic fibroblast growth factor in cardiac myocytes: expression and effects; E. Kardami, R.R. Padua, K.B.S. Pasumarthi, Lei Liu, B.W. Doble, S.E. Davey, P.A. Cattini. 6. Growth factor signal transduction in the cardiac myocyte: Functions of the serum response element; M.D. Schneider, T. Brand, R.J. Schwartz, W.R. MacLellan. 7. Effects of growth factors on human cardiac myocytes; B.I. Goldman, J. Wurzel. Section three: Growth Factors and Angiogenesis. 8. Growth factors and development of coronary collaterals; H.H. Sharma, R. Zimmerman. 9. The role of growth factors in angiogenesis; R.J. Schott, L.A. Morrow. Section four: Growth Factors and Atherosclerosis. 10. Atherosclerosis and platelet-derived growth factors; G.A.A. Ferns, C. Rutherford. 11. Effects of transforming growth factor beta on vascular smooth muscle cell growth; P.I. Weissberg, D.J. Grainger, J.C. Metcalfe. 12. Some aspectsof growth factor signal transduction in vascular smooth muscle cells; A.C. Newby, N.P.J. Brindle. 13. Basic FGFs role in smooth muscle cell proliferation: A basis for molecular atherectomy; W. Casscells, D.A. Lappi, A. Baird. Section five: Growth Factors and Cardiovascular Disease: Clinical and Therapeutic Implications. 14. Role of transforming growth factor β in cardioprotection of the ischemic-reperfused myocardium; A.M. Lefer. 15. Platelet-derived growth factor release after angioplasty; P. Macke Consigny. 16. Platelet-derived growth factor receptor activity induced by vascular injury; G.E. Bilder. 17. Growth factors and hypertension: Implications of growth factor function in vascular remodelling; A.K. El Amrani, F. El Amrani, P. Cummins. 18. Transforming growth factor β and carcinoid heart disease; J. Waltenberger. Section six: Growth Factor Effects on the Myocardium. 19. Adrenergic stimulation and growth factor activity; C.S. Long, P.C. Simpson. 20. Effects of transforming growth factor β on cardiac fibroblasts; M. Eghbali. 21. Transforming growth factor β's and cardiac development; R.J. Akhurst, M. Dickson, F.A. Millan. Index.