Table of Contents

1. Nucleic acid adjuvants: towards an educated vaccine Jasper G. van den Boorn, Winfried Barchet and Gunther Hartmann
2. Structure-based design for high-hanging vaccine fruits Johannes P.M. Langedijk and Jaap W. Back
3. Mechanisms of peptide vaccination in mouse models: tolerance, immunity and hyper-reactivity Thorbald van Hall and Sjoerd H van der Burg
4. Experience with synthetic vaccines for cancer and persistent virus infections in non-human primates and patients Esther D. Quakkelaar and Cornelis J.M. Melief
5. Malaria vaccine development using synthetic peptides as a technical platform Giampietro Corradin, Nora Céspedes, Antonio Verdini, Andrey V. Kajava, Myriam Arévalo and Sócrates Herrera
6. Enhancing cancer immunotherapy by intracellular delivery of cell penetrating peptides and stimulation of pattern-recognition receptor signaling Helen Y. Wang and Rong-Fu Wang
7. TLR ligand-peptide conjugate vaccines: towards clinical application Gijs GP Zom, Selina Khan, Dmitri V Filippov, Ferry Ossendorp
8. Behaviour and function of Tissue-resident Memory T cells Silvia Ariotti, John B. Haanen and Ton N. Schumacher
9. Rational Design of Vaccines: Learning from Immune Evasion Mechanisms of Persistent Viruses and Tumors Ramon Arens