This issue of Physical Medicine and Rehabilitation Clinics devoted to Life Care Planning is Guest Edited by Michel Lacerte, MD, Richard Paul Bonfiglio, MD, and Cloie B. Johnson, M.Ed., ABVE, CCM. This issue will focus on the long-term care of a patient’s rehabilitation, typically after a major life event. Articles in this issue will focus on the life care planning of patients with spinal cord injury, acquired brain injury, spinal pain, Cerebral Palsy, neuropathic pain, and life care planning for amputees. Other articles in this issue include: The Life Care Planning Process; The Physiatrist’s Role in Life Care Planning; Life Expectancy Determination; and Vocational Rehabilitation and Work Life Expectancy.