A Balanced Omega-6/Omega-3 Fatty Acid Ratio, Cholesterol and Coronary Heart Disease

A Balanced Omega-6/Omega-3 Fatty Acid Ratio, Cholesterol and Coronary Heart Disease

by A. P. Simopoulos
     
 

For more than half a century, the relationship between dietary factors and coronary heart disease (CHD) has been a major focus of health research. Contrary to the established view, current data suggest that dietary cholesterol is not a primary factor of or causes heart disease with the possible exception of the genetic forms of familial hypercholesterolemias. For

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Overview

For more than half a century, the relationship between dietary factors and coronary heart disease (CHD) has been a major focus of health research. Contrary to the established view, current data suggest that dietary cholesterol is not a primary factor of or causes heart disease with the possible exception of the genetic forms of familial hypercholesterolemias. For instance, recent clinical trials evaluating the effect of cholesterol-lowering drugs on the development of chronic heart failure, diabetes and stroke have yielded disappointing results. On the other hand, an unbalanced omega-6/omega-3 fatty acid ratio and a cholesterol intake not consistent with the amount during evolution seem to be causal factors in the development of CHD. A panel of international experts in genetics, nutrition, fatty acid, cholesterol, metabolism and coronary heart disease has contributed to this publication, summarizing and critically discussing for the first time the importance of evolutionary aspects of diet, the omega-6/omega-3 fatty acid ratio and cholesterol intake relative to health and CHD. They also propose measuring blood fatty acids in the population in order to define the risk of CHD and other chronic diseases. This book will be of interest to physicians (cardiologists, gerontologists, and pediatricians), nutritionists, dieticians, health care providers, scientists in industry and government and policy makers.

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Editorial Reviews

Doody's Review Service
Reviewer: Amy Hess-Fischl, MS, RD, LDN, BC-ADM, CDE (University of Chicago Medical Center)
Description: This is a compilation of presentations from a satellite workshop of the Second Congress of the International Society of Nutrigenetics/Nutrigenomics that was held in Geneva, Switzerland, in October 2008. It includes 10 papers devoted to several topics, including omega-6 and omega 3 fatty acids, dietary cholesterol, and lipid nutrition.
Purpose: The purpose is to discuss the papers that were presented at the satellite workshop and the book delivers on that promise, by providing in-depth information from each of the presentations.
Audience: The book is intended primarily for healthcare providers involved in the care of individuals with, or at risk for, coronary heart disease. This is a high level discussion about these topics that assumes readers have a good knowledge base about the current research. It may be interesting for students to read, but it probably is not appropriate as a textbook. The authors of the papers are respected researchers in the field.
Features: The first few papers provide an in-depth review of omega-6 and omega-3 fatty acid ratios. The others focus on blood and dietary cholesterol as well as lipid nutrition. There are very high level explanations of mechanisms of action throughout each paper. In their presentations, the researchers include their own opinions about the current research as well as future research needs. They all provide interesting reviews and give fascinating insight into potentially new research. However, this is not necessarily an all-encompassing view of the current thinking about lipid research.
Assessment: This is an excellent review of lipid nutrition and omega-6 and omega-3 fatty acid research for those who have a strong understanding of the current research. The book summarizes the satellite symposium very well.

Product Details

ISBN-13:
9783805592246
Publisher:
Karger, S. Inc.
Publication date:
08/12/2009
Series:
World Review of Nutrition and Dietetics Series
Pages:
126
Product dimensions:
7.60(w) x 10.20(h) x 0.50(d)

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