A History of Organ Transplantation: Ancient Legends to Modern Practice

Overview

Foreword by Clyde Barker and Thomas E. Starzl

A History of Organ Transplantation is a comprehensive and ambitious exploration of transplant surgery—which, surprisingly, is one of the longest continuous medical endeavors in history. Moreover, no other medical enterprise has had so many multiple interactions with other fields, including biology, ethics, law, government, and technology. Exploring the medical, scientific, and surgical events that led to modern transplant techniques,...

See more details below
Hardcover (1)
$54.15
BN.com price
(Save 16%)$65.00 List Price

Pick Up In Store

Reserve and pick up in 60 minutes at your local store

Other sellers (Hardcover)
  • All (10) from $58.99   
  • New (7) from $58.99   
  • Used (3) from $83.80   
Sending request ...

Overview

Foreword by Clyde Barker and Thomas E. Starzl

A History of Organ Transplantation is a comprehensive and ambitious exploration of transplant surgery—which, surprisingly, is one of the longest continuous medical endeavors in history. Moreover, no other medical enterprise has had so many multiple interactions with other fields, including biology, ethics, law, government, and technology. Exploring the medical, scientific, and surgical events that led to modern transplant techniques, Hamilton argues that progress in successful transplantation required a unique combination of multiple methods, bold surgical empiricism, and major immunological insights in order for surgeons to develop an understanding of the body’s most complex and mysterious mechanisms.  Surgical progress was nonlinear, sometimes reverting and sometimes significantly advancing through luck, serendipity, or helpful accidents of nature.
      The first book of its kind, A History of Organ Transplantation examines the evolution of surgical tissue replacement from classical times to the medieval period to the present day. This well-executed volume will be useful to undergraduates, graduate students, scholars, surgeons, and the general public. Both Western and non-Western experiences as well as folk practices are included. 

Read More Show Less

Editorial Reviews

From the Publisher
"This beautiful history . . . gives a sense of the vivacity of scientific experience, its errors and insights, and the way in which cultural traits, individual lives, and technical knowledge combine to create a field of clinical medicine. . . . Those who are willing to read David Hamilton will find a well-written and exciting history—physiology and medicine, and the lives of those who pursue them, will seem more fascinating, and science more wild and willful."
—Times Literary Supplement (TLS)

“A comprehensive, authoritative history of a transformative field of medicine. Well crafted and global in scope. . . . scholars and historians of medicine will find Hamilton a thorough guide to a complex subject.”

—Library Journal

“Written for the average reader without ignoring scientific detail.”

—Pittsburgh Post-Gazette

“David Hamilton has written a history of transplantation that is unmatched in its scope, perceptiveness and readability. The masterly account he has crafted comes at an appropriate time, since organ transplantation has now become widely accepted, as the best therapy for many otherwise fatal diseases. The surgeon-author of this book has watched and participated in many of the events as the field evolved over the last half century. Having looked back as an informed insider, he has added his historian’s detachment and insight to the narrative. . . . Hamilton is clear that, in surgery at least, there is no single method of discovery but rather a rich variety of methods. Adding to his text are extensive scholarly citations that give a helpful road map into the vast literature on organ transplantation. As this book clearly shows, developing transplantation as a clinical service was not simply a surgical matter, limited to the attainment of technical success. Hamilton describes the crucial multiple influences, helpful and otherwise, that came into play.”
—Clyde Barker, M.D. and Thomas E. Starzl, M.D., Ph.D., from the Foreword

“What a superb book! Hamilton, a retired transplant surgeon . . . is not content merely to list achievements in organ transplantation from antiquity through the end of the 20th century. Instead, he has written a wide-ranging, comprehensive evaluation of the factors—inculding luck—that account for this intellectually imposing specialty. This is probably the first history of the field that will make it look complete and recognizable to practitioners. Historians of medicine wiill admire the book for its critical use of primary documents. Those who study immunology or hematology or their histories will also profit greatly from it. . . a pleasure to read. Hamilton is a master of style, and readers will not be disappointed. No serious library should be without this book. Summing up: Essential."
—Choice

“I have learnt a huge amount from this book, and it is humbling to realise once again how privileged I am as a transplant surgeon to be part of this legacy spanning several hundred years, giving new meaning to the phrase ‘standing on the shoulders of giants’.”

—Lorna Marson for Surgeons’ News

Library Journal
Retired transplant surgeon Hamilton (medical history, St. Andrews Univ. Medical Sch., Scotland; The Healers: A History of Medicine in Scotland) has written a comprehensive, authoritative history of a transformative field of medicine. He traces the origins of organ transplantation to skin grafting procedures that restored the noses of criminals and political prisoners punished with disfiguring amputations in fifth century B.C.E. India. This technique was briefly resurrected by an Italian surgeon in the 16th century and later rediscovered in India by British colonists in the early 19th century. As Hamilton illustrates, the episodic history of skin transplants parallels the development of transplant surgery as a whole. Only by the 1970s were the technology, cell and genetic science, pharmacology, and legal framework available to match the skills of surgeons. With all the pieces finally in place, lifesaving transplantations of major organs became relatively routine. VERDICT This history is well crafted and global in scope. Although its length and detail may daunt general readers, scholars and historians of medicine will find Hamilton a thorough guide to a complex subject.—Kathy Arsenault, St. Petersburg, FL
Read More Show Less

Product Details

  • ISBN-13: 9780822944133
  • Publisher: University of Pittsburgh Press
  • Publication date: 6/28/2012
  • Edition description: 1
  • Pages: 560
  • Sales rank: 986,321
  • Product dimensions: 7.00 (w) x 10.00 (h) x 1.50 (d)

Meet the Author

David Hamilton is a retired surgeon and honorary senior lecturer at the Medical School of St. Andrews University, where he teaches medical history. He is the author of two previous books, The Monkey Gland Affair and The Healers: A History of Medicine in Scotland.

Read More Show Less

Table of Contents

Foreword Clyde F. Barker Thomas E. Starzl vii

Acknowledgments xi

Introduction: Toward the Impossible xiii

1 Early Transplantation 1

2 The Eighteenth Century 31

3 The Reawakening 49

4 Clinical and Academic Transplantation in Paris 65

5 The Beginning of Organ Transplantation 88

6 The "Lost Era" of Transplantation Immunology 105

7 Anarchy in the 1920s 126

8 Progress in the 1930s 154

9 Understanding the Mechanism 173

10 Experimental Organ Transplantation 195

11 Transplantation Tolerance and Beyond 221

12 Hopes for Radiation Tolerance 254

13 The Emergence of Chemical Immunosuppression 269

14 Support from Hemodialysis and Immunology in the 1960s 296

15 Progress in the Mid-1960s 314

16 Brain Death and the "Year of the Heart" 340

17 The Plateau of the Early 1970s 359

18 The Arrival of Cyclosporine 380

19 Waiting for the Xenografts 413

Conclusion: Lessons from the History of Transplantation 423

Notes 431

Bibliographic Essay 527

Index 539

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)