The pioneer period of in vitro fertilization forms the backdrop for Karp’s promising first in a new series set in the Pacific Northwest. In 1977, obstetrician Colin Sanford aspires to be the first person to produce a viable baby through this innovative procedure. Aided by embryologist Giselle Hearn, Sanford successfully treats an infertile patient, Joyce Kennett. But before he can announce the birth of Joyce’s son, her husband, James, shoots Giselle dead and then himself. While trying to determine what triggered the murder-suicide, Det. Bernie Baumgartner discovers an additional mystery: the disappearance of Giselle’s laboratory supervisor. A duel of wills and wits ensues between the detective and Sanford, who aims to guard his reputation and avoid scandal. Karp (The Ragtime Fool), who as a young doctor was a witness to the race to produce the first IVF baby, tempers his well-constructed whodunit with dashes of science and a hint of poignancy. (Dec.)
A Perilous Conception
Narrated by Traber Burns, Sean Runnette
Larry KarpUnabridged — 8 hours, 32 minutes
A Perilous Conception
Narrated by Traber Burns, Sean Runnette
Larry KarpUnabridged — 8 hours, 32 minutes
Audiobook (Digital)
Related collections and offers
Overview
It's 1976. Despite fierce international controversy over whether in vitro fertilization (IVF) should ever be performed in humans, doctors around the world race to be first to produce a baby through this procedure.
Dr. Colin Sanford, a brilliant, ambitious obstetrician in the Pacific Northwest city of Emerald, has a plan. He recruits Dr. Giselle Hearn, an experienced laboratory geneticist-embryologist at the university who's frustrated by the ultraconservative policies of her department chairman. Drs. Sanford and Hearn, working secretly, set out to put their names in history books. Unfortunately, a secret that big is hard to keep, and Alma Wanego, Dr. Hearn's lab supervisor, catches on and demands a blackmail payment. Several months later, Dr. Sanford's patient, Joyce Kennett, gives birth to a healthy boy, and Sanford prepares to make an announcement at a press conference. But before that happens, Joyce Kennett's marginally-schizophrenic husband kills Dr. Hearn and then himself.
Police detective Bernie Baumgartner's investigation is hampered by pressure from influential people at the university who want to control sensationalism that might harm the institution. The chief of police chalks it up to the work of a mentally unstable man who may have forgotten to take his medication and considers the case closed. But dogged, tenacious Baumgartner suspects that Sanford and Hearn were in fact doing IVF, that they succeeded with the Kennetts, and that murder, suicide, and other crimes were the fallout.
A double cat-and-mouse game develops between doctor and detective, and as stakes escalate, truth becomes an increasingly evasive commodity.
Editorial Reviews
"A clever, intricate medical mystery with plenty of twists, an inventive touch with metaphors, and an ample helping of wit."
"A former doctor who delivered the first baby conceived through IVF in the Pacific Northwest, Karp (First, Do No Harm in the “Music Box Mystery” series) brings a fresh topic to the medical thriller. Readers will be delighted with his new detective’s debut. Pages will fly by as his action-packed cat-and-mouse chase draws to an unexpected conclusion." —Library Journal
"Alternating first-person narratives from the self-important surgeon and the hard-boiled sleuth add texture to this series kickoff from Karp ( The King of Ragtime , 2008, etc.). Well paced and intriguing." —Kirkus Reviews
"Don't miss this one - it is a definite keeper. The author does a fantastic job with these two main characters. You love them one minute and hate them the next." —Feathered Quill Book Reviews
"If you’re looking for a crime thriller to keep you on the edge of your seat right to the very last page, look no further. A Perilous Conception is just what the doctor ordered." — New York Journal of Books
"In A Perilous Conception Larry Karp provides a clever, intricate medical mystery with plenty of twists, an inventive touch with metaphors, and an ample helping of wit. As any writer knows, telling a story from more than one point of view is a tricky business, but Karp brings it off with aplomb, keeping his characters separate, distinctive . . . and interesting. And as an added bonus, the next time the subject of in vitro fertilization comes up at a cocktail party, you'll blow everybody's socks off." —Aaron Elkins, Edgar winner and author of The Worst Thing
"Karp ( The Ragtime Fool ), who as a young doctor was a witness to the race to produce the first IVF baby, tempers his well-constructed whodunit with dashes of science and a hint of poignancy."—Cevin Bryerman, Publishers Weekly
"Karp lays out a very entertaining puzzle for medical-mystery fans." —Barbara Bibel, Booklist
"Hot-button issues, ruthless ambition, human experimentation, blackmail, suicide, murder… A PERILOUS CONCEPTION delivers."—Kevin O'Brien, New York Times Best-selling Thriller Author
It's 1977 in a large city in the Pacific Northwest, and a hotshot obstetrician has paired up with a crackerjack lab professor to create what might just be the world's first successful in vitro fertilization (IVF) baby. But something goes horribly wrong when the baby's father kills the lab doc and then himself. Detective Bernie Baumgartner wants to know the motivation behind the crime, and he doesn't give up easily. The new mother is less than grief-stricken, and this puzzles him, as does the stonewalling obstetrician. With Baumgartner's bumbling persona hiding an intelligent and intuitive mind, these geniuses don't stand a chance. VERDICT A former doctor who delivered the first baby conceived through IVF in the Pacific Northwest, Karp (First, Do No Harm in the "Music Box Mystery" series) brings a fresh topic to the medical thriller. Readers will be delighted with his new detective's debut. Pages will fly by as his action-packed cat-and-mouse chase draws to an unexpected conclusion.
Detective Baumgartner finds himself with an unusual case: Dr. Colin Sanford recruited Dr. Giselle Hearn for a secret IVF collaboration that produced a healthy baby boy. But the controversial in-vitro fertilization was dwarfed by the news of Dr. Hearn’s murder by the birth mother’s schizophrenic husband, who also killed himself. Traber Burns and Sean Runnette’s polished performances richly characterize and contrast Sanford’s egotistical personality with Baumgartner’s hard-boiled persona as they alternate first-person points of view. Runnette’s delivery of Baumgartner’s crusty voice is especially believable. The portrayal of Baumgartner’s sidekick, Iggy, is laugh-out-loud funny when Iggy pours double-strength peroxide on Baumgartner’s fanny wound. This medical mystery is not to be missed. G.D.W. © AudioFile 2012, Portland, Maine
When a veteran detective investigates a baffling murder-suicide, he uncovers a medical morass and some profound ethical questions. Dr. Colin Sanford, an obstetric superstar at his hospital in metropolitan Emerald, Wash., is taken aback by the news that his colleague Dr. Giselle Hearn has been shot to death by James Kennett, the husband of one of his patients, in an apparent murder/suicide. Flashback to a year ago, when Sanford first meets Hearn, an expert geneticist somewhat restricted in her research because she works at a Catholic hospital. In 1976, the world of in vitro fertilization is nascent at best. Sanford's patients include James and Joyce Kennett, an infertile couple desperate for a child. Sanford, who has boundless ambition and, apparently, loose ethics, entices Hearn to work secretly with him on impregnating Joyce. Bernie Baumgartner, the veteran detective who's investigating the Kennett killings, enters the story even as Sanford's flashbacks continue. Sanford reluctantly admits to the reader that the process was not easy but reveals that Joyce gave birth to a healthy boy, whom she and James named Robbie. There'll be a spot of attempted blackmail by Hearn's colleague Alma Wanego, and plenty of spicy goulash and tart opinions served up by Bernie's Hungarian wife Irma. Alternating first-person narratives from the self-important surgeon and the hard-boiled sleuth add texture to this series kickoff from Karp (The King of Ragtime, 2008, etc.). Well paced and intriguing.
Product Details
| BN ID: | 2940169911787 |
|---|---|
| Publisher: | Blackstone Audio, Inc. |
| Publication date: | 12/06/2011 |
| Series: | Detective Baumgartner , #1 |
| Edition description: | Unabridged |
Read an Excerpt
A Perilous Conception
By Larry Karp
Poisoned Pen Press
Copyright © 2011 Larry KarpAll right reserved.
ISBN: 978-1-59058-975-5
Chapter One
Thursday, April 28, 1977 Sanford
One last look in the hall mirror. I straightened my tie, brushed my hand over that unruly clump of hair above my right ear. Should I be suave and assured, or would I come off better as wide-eyed and enthusiastic, maybe even a little eccentric? As I glanced at the gray fabric-covered log book in my hand, I caught the reflection of my smile in the mirror. Perfect. Cool, self-possessed, yes. Suave was the way to go.
I didn't need to check my watch, but did anyway. Couple of minutes past one, almost an hour till the press conference. By five o'clock, I'd be on the local news, right at the top, and tomorrow morning, my face would be on every screen from San Francisco to Timbuktu. Well, my face and Giselle Hearn's, fair enough. I'd make sure to say I couldn't have done it without her, but there'd be no doubt who'd been the project leader, and who, the co-worker. I smiled again.
Good move, borrowing Giselle's lab log last night, then canceling my appointments and staying home this morning. My office staff would've been driving me nuts, wanting to know what all the fuss was about. Instead, I'd put in five solid hours, studying the log and my pile of reprints from Nature, Lancet, and The American Journal of Obstetrics and Gynecology. For more than a year, I'd been keeping up with that literature, but I wanted to be sure I had the material down cold, every detail. I couldn't afford a misstep.
I walked out into the corridor, took the elevator down to the lobby, clapped Albert, the doorman, on the arm. "Hey, Doc," Albert rumbled. "Them Seadogs gonna win today?"
The Emerald Seadogs, Major League Baseball's brand new representatives in the Pacific Northwest, were supposedly starting their existence under a lucky sign, double-sevens. But before the end of the first month of that auspicious 1977 season, the Seadogs were already hopelessly in the cellar, couldn't win for losing. "Don't know, Albert. I only bet on horses, but if I did bet baseball, I think I'd keep my money in my pocket on that one." The old doorman cackled.
With its long winters of short, gray, drizzly days, Emerald is the suicide capital of the country. This past season had been a prizewinner, barely a glimpse of sun between Christmas and Easter. But today, the sky was a glorious blue, not a cloud anywhere, and I threw back my head to take in the warmth of the midday sunlight. From this day on, that sun would shine on me, nonstop. Patients would clog my office. I'd see my photo in newspapers, magazines, on the tube. My name would be front and center in articles and popular histories; I'd get whole chapters in reproductive medicine textbooks. Rotary Club presidents and chairmen of university departments would book me for talks. It was not beyond reason to expect that one day I'd get a call to come give a speech in Stockholm. My parents would finally have to hand it to me. Their son was about to become a legend in medicine.
Most of my colleagues lived in big houses in one or another of the fancy Emerald suburbs, which entitled them to drive nearly an hour to and from work, sometimes in the middle of the night. Not for me. An easy seven-minute walk, and I was at my office in the Emerald Medical Tower, linked by skybridges to Puget Community Hospital on one side, and the new glass-and-steel Washington Public University Medical Complex on the other.
I strode into the Tower Lobby, past patients, some in wheelchairs, or making their way slowly on canes. White-coated doctors talked to white-capped nurses. Techs pushed blood-draw carts and EKG machines. For all the attention they weren't giving me, I could've been walking along a sidewalk in midtown Manhattan, but that was about to change. Tomorrow, people on all sides would stop, point, whisper to their companions, "Hey, isn't that Dr. Colin Sanford? You know, the guy ..."
As I walked into my waiting room, a buzz of talk went silent. Lettie and Sally, the receptionists, Kinsey and Ruth Ellen, the nurses, Megan, the nurse-practitioner, stood in a circle in front of the reception counter. One look at me, and they froze in place, a body with five chalky faces, five open mouths and ten saucer-eyes. Barbara Renfro, the office manager, stood off from the others, stone-faced, leaning against the end of the counter. Her Adam's apple bobbed up, down, up again.
The room reeked of trouble. Had one of my patients keeled over with a pulmonary embolism? Did the pediatricians find a serious birth defect in a baby? Nah, either way, a nurse would have called my beeper. I looked past the mob to Barbara. "Got something to tell me?"
She motioned me down the hall past reception, to my consulting office.
I followed her along the corridor, into the office, closed the door. She rested a hand on my arm. "Oh, Dr. Sanford. Dr. Hearn is ... dead."
"Dead? No."
"She was shot. Murdered. In her lab, a little while ago. And ..."
"What, Barbara?"
"Mr. Kennett did it."
"Mr. Kennett? Why on earth would he ever—"
"And after he killed Dr. Hearn, he shot himself. A Detective Baumgartner called here not five minutes ago, looking for you. He got your name off Mr. Kennett's newborn-nursery ID bracelet. I told him we expected you any time now, and he said he wants you to go over to the lab immediately to talk to him."
I pride myself on keeping a cool head in emergencies. "I'll get over there ASAP. Would you please cancel the press conference for me?"
"Of course." She took a step away. "Dr. Sanford ... did the conference have something to do with the Kennetts?"
I nodded.
As she walked out of the office, I stared at the log book in my hand. Doubly fortunate now that it wasn't sitting in a desk drawer in Giselle's office, where the cops would find it. It was my ticket to the future, but it also contained seeds for disaster, which I'd stumbled onto the night before. No reporter at the press conference, rushing to get the story out, would have looked inside that log, but the scientists we'd beaten to the finish line would want to review it, and to say the least, some of the material could be embarrassing. I thought I knew what to do about it, and had figured to sit down with Giselle after the conference to get her on board. But that idea had been knocked into a cocked hat along with the conference. In any case, the log had to go someplace out of sight for the time being, absolutely-positively safe where no one would think of checking.
I scanned the room. Stash it in my desk? That'd be the first place anyone would look. Two walls of bookshelves, filled with medical textbooks, monographs, and leather-bound journals. Good camouflage, but not good enough. The faux-woodgrain metal file cabinet next to my desk? Negative. A file cabinet would be Number Two on any search, right after my desk ... but wait, here's an idea. I stepped across the room, lowered a shoulder, tipped the cabinet. Below the bottom drawer was a nice little recess. Good. I tossed the log book into the cavity, gave a short silent thanks for all those after-work hours at the gym, then lowered the cabinet.
I hung my suit jacket on a hook behind the door, grabbed a white coat from an adjacent hook, shrugged it on, and rushed out, through the waiting room, into the hallway, down the corridor to the skybridge. I could deal with a little delay in my plans. First things first, and the first thing had to be a talk with Joyce Kennett. Going to the lab and talking to the cops would need to settle for second.
Chapter Two
Sanford
I'm a doctor, an OBGYN. I opened my office in Emerald in 1965, and by 1970, my practice was the biggest in town. Patients knew when they came to me, they'd get the best care possible, and they'd get it directly from me. No partners, no interns, no med students. I always did have an eye for the main chance—no point denying the obvious—and during the late sixties, I saw laparoscopy was the coming thing in my field. And why not? Would you want your surgery performed through the customary five-inch slash in the breadbasket if it could be neatly accomplished via a thin optical instrument slipped through a tiny puncture into the abdomen? So I took myself off to Philadelphia to learn the procedure from the guru, Guiseppe Allegri, and I've got to tell you, Allegri was impressed. He said he'd never seen anyone with such a knack for the procedure. When I got back home, I wangled an interview with the medical editor of The Emerald Times, to tell the city all about Band-Aid surgery, now available right in its own back yard. My office phones didn't stop ringing for days.
Then, in the midseventies, federal research grants began to dry up. The University faculty panicked. None of them had ever dreamed of dirtying their hands by laying them on patients, but necessity really is a mother, and the professors started promoting themselves as super-specialists, the ultimate experts. What they didn't say was that hands-on care at the U would in fact be provided by residents and med students, and the professors' role would consist of initialing trainees' chart notes. But you can sell people anything, and I started to notice a patient here, a patient there, leaving my care to go to "The Northwest's Preeminent Medical Center." Which pissed me off, royally.
You've got to keep an eye on your opposition, so I was a regular at the Wednesday morning University OBGYN Grand Rounds, where professors, fellows, and residents honed their one-upsmanship skills, pontificating on esoteric topics. At the first session after Christmas break, in January, 1976, the speaker was Dr. Giselle Hearn, a PhD embryologist. The room was packed. Dr. Hearn talked about her experiments on the behavior of chromosomes at fertilization in mice, which she hoped would shed light on factors that cause errors during that process, and produce conditions like Down Syndrome. Near the end of the hour, she said she was convinced there would be no real breakthroughs until studies being carried out in other research centers on human gametes started to yield up critical information.
I didn't realize she'd flung a gauntlet until Gerry Camnitz flew to his feet, no small accomplishment given the size and weight distribution of L. Gerald Camnitz, MD. The Professor and Chairman of OBGYN had the look of an angry, red-faced walrus in a sharply-tailored gray suit, pink shirt, and narrow blue tie. "Dr. Hearn, this is not a public forum for departmental policy. It is an educational session. Kindly stick to your subject."
Hearn's face and body language told everyone in that room they were about to get a preview of the Bicentennial fireworks display. She blinked at Camnitz like a cow, offended at having gotten a gratuitous poke in the udder from a stick in the hand of a nasty little boy. "I've not gone off my topic, Dr. Camnitz. I've merely stated a matter of fact. If it happens to conflict with your prejudices, you might do well to reconsider."
I'd had no idea what was obviously running deep below the calm surface waters of the University OBGYN Department. A couple of medical students snickered. Camnitz silenced them with a glare, then turned back to Hearn. "All right, Dr. Hearn. Since you insist on pursuing this, I will restate my policy. We are not going to start down the slippery slope of experimentation on human embryos, not in my department. The ethical, moral, and legal implications are too uncertain. Would you propose to flush human beings down a sink when they're no longer of use to you? Would you be concerned even the slightest bit that attempts at in vitro fertilization might produce monstrously abnormal children?"
"I never said anything about in vitro—" Hearn began, but Camnitz shouted her down with, "This conference is over. Thank you all for coming." I thought he might follow that with an order for Hearn to go to the Dean's office and serve detention, but instead, he stormed out of the auditorium. There was a brief silence, followed by a sound like the swarming of a million angry bees. Don Gardiner, a young assistant professor, poked an elbow into my ribs. "Welcome to the halls of ivy."
I muttered, "Yeah," but I was thinking about in vitro fertilization and embryo replacement.
* * *
Not a week later, I was talking to Joyce and James Kennett, one of my infertility couples. They had what's called idiopathic infertility, which is doctor-talk for "I don't have a goddamn clue." Joyce's temperature records showed she ovulated right on schedule, every twenty-nine days plus or minus one. X-ray contrast studies indicated no blockage of her fallopian tubes. Her uterus was perfectly normal, inside and out. James' sperm were lively and quick. The couple hit the mattress at a frequency that should already have borne them a football team. Artificial insemination with James' sperm had been no more efficacious than the natural process.
They were both up tight, squirming in the chairs opposite my desk. Not unusual for infertility patients. They'd been trying for a year before they first came to see me, and I'd been working with them for an equal length of time. Two years of having every menstrual period be a bitter cup of dashed hopes does things to people, and in any case, this couple was predisposed to emotional problems.
James had a history of borderline paranoid schizophrenia, had been doing well for years on psychotherapy and medication, but he'd gotten himself fired from several retail clerk jobs after customers complained about what they took as insults or smart-alecky comments. This translated into endless bouts of relapsing financial pins and needles.
Joyce, a biology teacher at Emerald Community College, had the anatomy, physiology, and biochemistry of conception down pat, which made the couple's failure—her word, not mine—all the more galling. She'd tried a bunch of dietary manipulations and folk remedies, none of which were any more effective than traditional approaches.
I brought up the possibility of adoption, but the two of them shot that down in a hurry. Joyce insisted she was going to have "my own baby," no ifs, ands, or buts. "And it's going to be my baby, too," James barked. "No way some other guy's sperm is going to get her pregnant, not if I have anything to say about it."
Joyce rested a hand on his arm, something I'd seen her do before when he looked like he might be about to lose it.
Once I saw his muscles relax, I reviewed the past eleven months of investigations and treatments, and was about to launch into an explanation of a journey through the terra incognita of infertility, when Joyce gave James a look that brought me up short. It asked, "Are you ready?"
He nodded.
Joyce turned back to me. "We've decided to go to the University."
Like a slap in the face. I was stunned. "Why?"
"We thought it would be a good idea to see one of the infertility specialists there."
I shook my head. "I guess you can do that, but they don't know anything I don't know. I read the same journals they do, and attend all kinds of conferences at the U and around the country."
James pulled at the back of his collar. Joyce sat a little straighter in her chair. "They work in this field all the time, but it's only a part of your practice," she said. "Maybe there's some new research that isn't even published yet."
They were going, no question. Infertility patients are like trains with disabled brakes. They wanted the benefit of new research. Were they thinking of in vitro fertilization? They weren't about to get that at the U, though, were they?
But they couldn't get it from me, either. I swallowed bile, got up, and extended my hand. "I wish you luck," I said. "Keep in touch. If they help you conceive, I'll certainly want to know the details."
James nearly fell over his feet, thanking me for trying to help. He pumped my hand as if he expected to see water gush out of my mouth. Joyce was cooler, but still cordial. "I'll definitely let you know," she said. "And if we're successful, I'd like to come back and have you take care of my pregnancy and delivery."
(Continues...)
Excerpted from A Perilous Conception by Larry Karp Copyright © 2011 by Larry Karp. Excerpted by permission of Poisoned Pen Press. All rights reserved. No part of this excerpt may be reproduced or reprinted without permission in writing from the publisher.
Excerpts are provided by Dial-A-Book Inc. solely for the personal use of visitors to this web site.
Videos
