A Perinatal Strategy For Preventing Adult Disease: The Role Of Long-Chain Polyunsaturated Fatty Acids / Edition 1

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This book proposes that fetal growth retardation and low-grade systemic inflammation can be prevented by perinatal supplementation of long-chain polyunsaturated fatty acids (LCPUFAs). Evidence for this hypothesis is presented and discussed in detail, along with possible mechanisms by which these substances produce beneficial actions. Finally, it is suggested that provision of adequate amounts of LCPUFAs during the perinatal period prevents insulin resistance, obesity, type 2 diabetes mellitus, hypertension, CHD, and Alzheimer's disease in the adult. Means of testing the hypothesis are also presented. Thus, the book suggests a simple and novel method of preventing diseases that are increasing in incidence in both the developed and developing worlds.

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Product Details

  • ISBN-13: 9781402070709
  • Publisher: Springer US
  • Publication date: 5/31/2002
  • Edition description: 2002
  • Edition number: 1
  • Pages: 208
  • Product dimensions: 9.21 (w) x 6.14 (h) x 0.50 (d)

Table of Contents

Preface. 1. Introduction. Fetal/Perinatal imprinting on later life. 2. Perinatal origins of adult disease. Obesity. 3. Perinatal origins of adult disease. Insulin resistance and Diabetes mellitus. 4. Perinatal origins of adult disease. Hypertension. 5. Perinatal origins of adult disease. Coronary heart disease. 6. Metabolic Syndrome X and low-grade systemic inflammation. 7. Long-chain polyunsaturated fatty acids in adult diseases: A hypothesis. 8. Breast-feeding. Composition and benefits. 9. Long-chain polyunsaturated fatty acids. Metabolism, physiology and clinical significance. 10. A perinatal strategy to prevent adult diseases: The Role of long-chain polyunsaturated fatty acids. Clinical implications and testing the hypothesis. Index.

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