A Statistical Approach to Genetic Epidemiology: Concepts and Applications / Edition 2

A Statistical Approach to Genetic Epidemiology: Concepts and Applications / Edition 2

by Andreas Ziegler, Inke R. Konig
     
 

This is the second edition of the successful textbook written by the prize-winning scientist Andreas Ziegler, former President of the German Chapter of the International Biometric Society, and Inke K?nig, who has been teaching the subject over many years.
The book gives a comprehensive introduction into the relevant statistical methods in genetic epidemiology. The… See more details below

Overview

This is the second edition of the successful textbook written by the prize-winning scientist Andreas Ziegler, former President of the German Chapter of the International Biometric Society, and Inke K?nig, who has been teaching the subject over many years.
The book gives a comprehensive introduction into the relevant statistical methods in genetic epidemiology. The second edition is thoroughly revised, partly rewritten and includes now chapters on segregation analysis, twin studies and estimation of heritability. The book is ideally suited for advanced students in epidemiology, genetics, statistics, bioinformatics and biomathematics. Like in the first edition the book contains many problems and solutions.

Product Details

ISBN-13:
9783527324538
Publisher:
Wiley, John & Sons, Incorporated
Publication date:
05/24/2010
Edition description:
New Edition
Pages:
522
Product dimensions:
6.80(w) x 9.60(h) x 1.20(d)

Table of Contents

INTRODUCTORY GENETICS
Molecular Genetics
Formal Genetics
Genetic Markers
Data Quality
LINKAGE ANALYSIS AND FAMILY STUDIES
Genetic Map Distances
Model Based Linkage Analysis
Model Free Linkage Analysis for Binary Traits
Model Free Linkage Analysis for Quantitative Traits
Family Studies not Involving Genetic Markers
ASSOCIATION ANALYSIS
Fundamental Concepts of Association Analyses
Association Analysis with Unrelated Individuals
Family Based Association Analysis
Haplotypes
GWAs

Appendix
Solutions
References

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