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From The CriticsReviewer: Carol Macmillan, MD, FRCP (C)(University of Illinois at Chicago College of Medicine)
Description: This book provides the proceedings of the seventh of a series of Pediatric Neurology meetings sponsored by the Italian-based Mariani Foundation. A series editor ensures continuity between publications and this volume has its own three editors.
Purpose: This book is intended to underscore the interaction between clinical and basic sciences methodologies in order to optimize patient care and to deepen knowledge of the neurobiology of cerebral dysplasia. That a wide knowledge base in understanding cerebral dysplasia is of major importance does not need to be underscored; the book addresses this issue exhaustively.
Audience: The multiple authors, many of whom are recognized authorities in their respective fields, target this book to basic and clinical neuroscientists. It would be most relevant to adult and pediatric neurologists, especially epileptologists, and to basic scientists working in the field of cerebral dysplasia.
Features: The book presents a contemporary statement of what is known about the neurobiology, epileptology, neuroimaging, neuropathology, and neurogenetics of cerebral dysplasia in six parts. Available animal models are discussed, and surgical approaches to seizure management are discussed. Dr. Dobyns' chapter on the genetic basis of malformations of neuronal migration is especially exciting, and the reproduction of MRI films and multiple well-chosen gross and light microscopy figures are outstanding. The use of some color plates would have added to the visual impact of the book.
Assessment: This is a book of excellent quality that fills a unique niche. It is very thorough but nonetheless readable, and would be a helpful addition to the teaching libraries of neurology, child neurology, and epilepsy programs.