Adenosine Receptors: Therapeutic Aspects for Inflammatory and Immune Diseases

by Gyorgy Hasko (Editor), Bruce N. Cronstein (Editor), Csaba Szabo (Editor)

Overview

After a century of research, several lines of evidence now indicate that the ability of adenosine to directly control inflammatory cells has a major impact on the functions of the inflammatory and immune systems. Consequently, many promising therapeutic approaches are beginning to emerge that focus on the modulation of adenosine, including the deve

Product Details

ISBN-13:	9781040201817
Publisher:	CRC Press
Publication date:	07/20/2006
Sold by:	Barnes & Noble
Format:	eBook
Pages:	363
File size:	8 MB

About the Author

Gyorgy Hasko, Bruce N. Cronstein, Csaba Szabo

Table of Contents

Introduction. Adenosine Receptor Pharmacology. Regulation of Macrophage Function by Adenosine Receptor Engagement. Anti-inflammatory Effects of Inosine. Regulation of Adenosine Receptor Expression in Inflammation. A2a Adenosine Receptors in Ischemia. Adenosine, Toll-like Receptors, and Angiogenesis. Adenosine Signaling and Lung Fibrosis. Adenosine and Endothelial Cell Function. Regulation of Peripheral Inflammation by Spinal Adenosine. Adenosine, Hypoxia, and Immunity. Adenosine Regulation of Dendritic Cell Function. A2b Receptors in Intestinal Epithelial Cells. Adenosine Receptors in Multiple Sclerosis. Adenosine Receptors in Infectious Disease. Adenosine, Tumors, and Immunity. Adenosine in Atherosclerosis. Adenosine in Neuroimmunomodulation.

Editorial Reviews

"… written by a number of prime experts in the field. … highly recommended to readers who are interested in the pharmacology of adenosine receptors."

– Christa E. Muller, PharmaCenter Bonn, Germany in ChemMedChem, 3, 2008

From the Publisher