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Adult Stem Cells / Edition 1

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Overview

This comprehensive review of our current understanding of adult stem cell types and their regulation examines the derivation, characterization, and utility of adult stem cells found in skeletal muscle, dental pulp, prostate, kidney, the eye, inner ear, and other tissues. The authors pay special attention to adult stem cell plasticity and their utility in normal tissue homeostasis, as well as their applications in regenerative medicine.

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Editorial Reviews

From the Publisher
"This beautiful, hardcover book features glossy pages, exquisite color plates, and expert technical writing. Chapters include informative line drawings, photomicrographs, and an extensive bibliography. The diversity of topics will certainly capture the attention of a wide audience of readers. The book is compact and very readable. I enjoyed this book, and was surprised by the attention focused on different types of adult stem cells. The topic is timely. This book hopefully will be a stimulus for new researchers to enter the field. " -Doody's Health Sciences Book Review Journal

"This book contains an extensive review of liver stem cell research, including experimentation with extrahepatic tissue and sites. I would highly recommend this book for medical libraries as well as academic libraries at institutions with graduate programs in genetics, biochemistry, cell biology, neuroscience or molecular biology." -E-STREAMS

Doody's Review Service
Reviewer: Bruce A. Fenderson, PhD (Thomas Jefferson University)
Description: This book provides a comprehensive review of the field of adult stem cell research. This is an exciting new field of study, with potential application to transplantation biology, cancer biology, and regenerative medicine. This book includes 12 chapters on diverse topics ranging from spermatogenic stem cells, to adult liver stem cells, to mammary epithelial stem cells. Each author describes the identification, characterization and therapeutic utility of these rare tissue-specific, multipotential stem cells.
Purpose: The overall goal of this book is to provide experienced and novice investigators the background information, essential laboratory findings, and key references necessary to conduct research in this field. Broad concepts and methodology are woven together. The contributions are up-to-date and provide readers with an overview of this emerging field. This is an important contribution to the literature.
Audience: This book is written for basic science and clinical researchers at all stages of training. Medical students, graduate students, and established investigators will enjoy reading it. The authors of the individual chapters are all experts in their field of study.
Features: This beautiful, hardcover book features glossy pages, exquisite color plates, and expert technical writing. Chapters include informative line drawings, photomicrographs, and an extensive bibliography. The diversity of topics will certainly capture the attention of a wide audience of readers. The book is compact and very readable.
Assessment: I enjoyed this book, and was surprised by the attention focused on different types of adult stem cells. The topic is timely. This book hopefully will be a stimulus for new researchers to enter the field. My only reservation is that the organ systems covered represent only partial picture of this rapidly expanding field. For example, it would have been useful to learn more about mesenchymal stem cells present in cord blood or multipotential stem cells in the brain. Controversy regarding evidence for plasticity in adult stem cell populations also was not addressed to my satisfaction. The potential for somatic cell fusion events makes the interpretation of stem cell transplantation studies difficult to interpret. This is a very readable book. The diversity of topics and attention to detail will make this useful to investigators interested in stem cell replication and differentiation.

3 Stars from Doody
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Product Details

  • ISBN-13: 9781617373923
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 12/1/2010
  • Edition description: Softcover reprint of hardcover 1st ed. 2004
  • Edition number: 1
  • Pages: 346
  • Product dimensions: 9.00 (w) x 6.00 (h) x 0.81 (d)

Meet the Author

Dr. Kursad Turksen is a stem-cell biologist with a passion for understanding epidermal stem cells' commitment and differentiation and their utility in regeneration. He has also been interested in the role of the Claudin family of tight junction proteins in cell lineage analysis and differentiation. He is the Editor-in-Chief of Stem Cell Reviews and Reports, as well as the Stem Cell and Regenerative Medicine book series.
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Table of Contents

Adult Stem Cell Plasticity
William B. Slayton and Gerald J. Spangrude

Spermatogonial Stem Cells
Dirk G. de Rooij

Stem Cells in Skeletal Muscle
Anna Polesskaya and Michael Rudnicki

Gene Therapy Using Muscle-Derived Stem Cells
Christopher Chermansky, Johnny Huard, and Michael B. Chancellor

Human Dental Pulp Stem Cells: Characterization and Developmental Potential
Stan Gronthos, Natasha Cherman, Pamela Gehron Robey, and Songtao Shi

Epithelial Stem/Progenitor Cells in Thymus Organogenesis
Hans-Reimer Rodewald

Adult Liver Stem Cells
William B. Coleman, Joe W. Grisham, and Nadia N. Malouf

Endothelial Progenitor Cells
Takayuki Asahara and Jeffrey M. Isner

Prostate Epithelial Stem Cells
Anne T. Collins and David E. Neal

Mammary Epithelial Stem Cells
Elizabeth Anderson and Robert B. Clarke

From Marrow to Brain
Josef Priller

Adult Retinal Stem Cells
Monica L. Vetter and Edward M. Levine

Multipotentiality of Iris Pigment Epithelial Cells in Vertebrate Eye
Mitsuko Kosaka, Guangwei Sun, Masatoshi Haruta, and Masayo Takahashi

Stem Cell Biology of the Inner Ear and Potential Therapeutic Applications
Thomas R. Van De Water, Ken Kojima, Ichiro Tateya, Juichi Ito, Brigitte Malgrange, Philippe P. Lefebvre, Hinrich Staecker, and Mark F. Mehler

Engineering the In Vitro Cellular Microenvironment for the Control and Manipulation of Adult Stem Cell Responses
Ali Khademhosseini and Peter W. Zandstra

Stem Cells As Common Ancestors: Somatic Cell Phylogenies From Somatic Sequence Alterations
Darryl Shibata

Index

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