Overview

Offering a holistic view of the development of drug delivery systems, Advanced Drug Delivery presents the essential aspects necessary to understand and apply for effective drug delivery fundamentals, including practical issues, integration of pharmaceutics, and molecular biology. A suitable text for graduate and advanced undergraduate students, the book is logically divided into four sections: fundamentals, delivery approaches, disease applications, and future directions. Discussing design, in vitro studies, ...
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Advanced Drug Delivery

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Overview

Offering a holistic view of the development of drug delivery systems, Advanced Drug Delivery presents the essential aspects necessary to understand and apply for effective drug delivery fundamentals, including practical issues, integration of pharmaceutics, and molecular biology. A suitable text for graduate and advanced undergraduate students, the book is logically divided into four sections: fundamentals, delivery approaches, disease applications, and future directions. Discussing design, in vitro studies, clinical evaluation, and regulatory approval, each chapter includes objectives and assessment questions.
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Product Details

  • ISBN-13: 9781118662847
  • Publisher: Wiley
  • Publication date: 8/26/2013
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 1
  • Pages: 530
  • File size: 13 MB
  • Note: This product may take a few minutes to download.

Meet the Author

ASHIM K. MITRA, PhD, is Chairman of Pharmaceutical Sciences at the University of Missouri-Kansas City. Dr. Mitra is also a University of Missouri Curators' Professor and has more than thirty years of experience in the field of ocular drug delivery and disposition. He has been the recipient of research awards from the NIH, AAPS, AACP, ARVO, and other pharmaceutical organizations.

CHI H. LEE, PhD, is Professor of Pharmaceutical Sciences at the University of Missouri-Kansas City, where he teaches undergraduate and graduate pharmacy courses. His research focuses on elucidation of pathological mechanisms and formulation development of microbicidal and cardiovascular devices.

KUN CHENG, PhD, is Associate Professor of Pharmaceutical Sciences at the University of Missouri-Kansas City. His research seeks to develop novel drug delivery systems for siRNA and small molecule drugs. Dr. Cheng is the recipient of the 2011 American Association of Pharmaceutical Scientists (AAPS) New Investigator Grant Award in Pharmaceutics and Pharmaceutical Technologies.

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Table of Contents

Part I: Introduction and Basics of Advanced Drug Delivery

1. Physiological Barriers in Advanced Drug Delivery

2. Solubility and Stability Aspects in Advanced Drug Delivery

3. The Role of Transporters and Efflux System in Drug Delivery

4. Biomaterials in Advanced Drug Delivery

Part II: Strategies for advanced drug delivery

5. Strategies of targeted delivery

6. Prodrug and bioconjugation

7. Nanoscale drug delivery systems

8. Stimuli-responsive strategies in advanced drug delivery

9. Implants

10. Aptamer

11. Nanofiber

12. Biomimetic self-assembling nanoparticles

13. Protein/peptide drug delivery

14. Delivery of nucleic acids

15. Delivery of vaccine

Part III: Translational research of advanced drug delivery

16. Regulatory Considerations and Clinical Issues in Advanced Drug Delivery

17. Advanced drug delivery in cancer therapy

18. Advanced drug delivery in cardiovascular diseases

19. Recent Advances in Ocular Drug Delivery

20. Advanced drug delivery against sexual transmitted diseases

21. Advanced drug delivery to the brain

Part IV: Future applications of advanced drug delivery in emerging research areas

22. Cell-based therapeutics

23. Biomedical Applications and Tissue Engineering of Collagen

24. Molecular Imaging of Drug Delivery

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