Advanced Free Radical Reactions for Organic Synthesis

by Elsevier Science

Overview

Free radical reactions have become increasingly important and a very attractive tool in organic synthesis in the last two decades, due to their powerful, selective, specific, and mild reaction abilities. Advanced Free Radical Reactions for Organic Synthesis reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions. The book usefully provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications it is therefore suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students. This title is the definitive guide to radical chemistry for all scientists.

Product Details

ISBN-13:	9780080443744
Publisher:	Elsevier Science
Publication date:	01/14/2004
Pages:	270
Product dimensions:	6.50(w) x 9.45(h) x (d)

About the Author

Dr. Togo obtained his Ph. D in 1983 under the supervision of Professor Shigeru Oae (sulfur chemist) at Tsukuba University. He became a post-doctoral fellow at University of Lausanne in Switzerland (1983 to 1984) and ICSN in CNRS (The late Professor Sir Derek H. R. Barton; Novel-Prize Winner) in France (1984 to 1985). He became a research associate at Tsukuba University in 1987 and then at the present university in 1989, where he became an associate professor in 1994 and then a full professor since 2005. His research interests are the chemistry of novel reactions with molecular iodine and trivalent iodines, and with free radicals for organic synthesis.

Table of Contents

What are free radicals
Functional group conversion
Intramolecular radical cyclizations
Intermolecular radical addition reactions
Alkylation of aromatics
Intramolecular hydrogen-atom abstraction
Synthetic uses of free radicals for nucleosides and sugars: Barton-McCombie reaction
Barton decarboxylation reaction with N-hydroxy-2-thiopyridone
Free radical reactions with metal hydrides
Stereochemistry in free radical reactions
Free radicals related to biology
Free radicals for green chemistry

What People are Saying About This

From the Publisher

This title is the definitive guide to radical chemistry for all scientists

Editorial Reviews

"The author has succeeded in presenting many facets of this very interesting area of chemistry in a highly engaging manner. As a result, anyone who wishes to familiarize themselves with the field of radical chemistry should take the time to look through Advanced Free Radical Reactions for Organic Synthesis." —ORGANIC CHEMISTRY, 2005

From the Publisher