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An advanced level volume for postgraduate students and researchers of genetics, cytogenetics biotechnology, biosciences, botany, and zoology which provides detailed coverage of mendelian, molecular, biochemical, immuno, human, mutagenesis, and evolutionary genetics. Concepts, principles and phenomena of genetics have been explained with the help of tables and figures including references, questions and numerical problems at the end of each chapter.
INTERALLELIC AND INTERGENIC INTERACTIONS Interallelic Interactions Intergenic Inheritance Totipotency Pleiotropy Homeostasis
NON-MENDELIAN INHERITANCE Extranuclear Inheritance Yeast Mitochondrial Genome Universality of Genetic Code Mitochondrial Genes and Diseases Maternal Effects Nucleocytoplasmic Interactions Extrachromosomal Inheritance Hybrid Dysgenesis
GENETICS OF SYMBIOSIS Commensalism, Mutualism, and Parasitism Kingdoms of Living Organisms Endosymbionts and Ectosymbionts Viruses in Bacteria Agrobacterium and Crown Gall Disease Nitrogen-Fixing Symbiosis Host-Parasite Interactions
RECOMBINATION IN DROSOPHILA MALES Complete Linkage in Drosophila Males Fold-Back Elements of Drosophila
GENE AMPLIFICATIONS Amplification During Differentiation and Development Amplification by Selection Amplification and Tumorigenesis Amplification of Transferred Genes Arrangement of Amplified Chromosomal DNA Random vs Directed Gene Amplification
GENETIC CONTROL OF FUNCTION Relationship Between Gene and Enzyme Genetic Control of Biochemical Reactions Relationship Between Genotype and Phenotype One Gene-One Enzyme Hypothesis One Gene-One Polypeptide Hypothesis One Cistron-One Polypeptide One Gene-One Primary Cellular Function Hypothesis Pseudogenes
GENE EXPRESSION AND ITS ANALYSIS Central Dogma and Its Reversal Gene Expression RNAs: Their Processing and Functions Self-Splicing or rRNA in Tetrahymena Genetic Code Transcriptional Elements Synergistic Gene Expression Environmental Effects and Gene Expression Hormones and Gene Expression Penetrance and Expressivity Phenocopies Alternative RNA Splicing Gene Silencing
GENETIC CONTROL OF PROTEIN SYNTHESIS Translation in Prokaryotes Translation in Eukaryotes Fate of Completed Proteins Protein Targetting Protein Secretion Molecular Chaperone
GENE REGULATION IN PROKARYOTES Terminology of Gene Regulation Mechanism of Gene Regulation in Prokaryotes Antisense RNA in Prokaryotic Gene Regulation Prokaryotic Gene Regulation by DNA Rearrangements Alternative Sigma Factors
GENE REGULATION IN EUKARYOTES AND MODELS OF GENE Is Operon Concept Applicable to Eukaryotes?
Short-Term Versus Long-Term Regulation Mechanisms of Gene Regulation in Eukaryotes Gene Regulation by Hormonal Action DNA Methylation and Gene Regulation Gene Control Levels in Eukaryotic Cells Models of Gene Regulation Transcriptional Initiation in Mammalian Genes CAT-and TATA-binding Transcription Factors Antisense RNA Strategies in Eukaryotes Molecular Zippers in Gene Regulation Regulation of Gene Expression by Small Molecules Histones as Repressors of Gene Expression Eukaryotic Gene Regulation Through DNA Rearrangements Artificial Gene Repressors Specificity in Eukayotic Gene Transcription
GENETIC ENGINEERING Restriction Endonucleases Gene/DNA Cloning Gene Transfer Methods Chromosome Walking/Jumping Libraries Minisatellites and Microsatellites Polymerase Chain Reaction Transposon-Mediated Gene Transfer High Density Molecular Maps DNA Fingerprinting LOD Score Applications of Genetic Engineering Hazards of Genetic Engineering Gene Targetting Transgenic Plants Transgenic Animals Expression and Stability of Genetically Engineered Genes Genetically-Modified Food Gene Chip Technology
GENE PATENTING Requirements of Patentability What Can Be Got Patented?
Patenting - An International Activity Requirements for Depositing a Culture Patenting for Life Forms Selling the Sequences Property Rights Controversies on Genetic Manipulations Patenting and Agricultural Industry Economic Grains Impact of Patenting on Less Developed Nations Proposed Amendments on Patents Act, 1970
MAPPING QUANTITATIVE TRAIT LOCI Reasons for Locating QTLs Linkage of a Quantitative Trait to a Major Gene Principle of QTL Mapping Advanced Backcross of QTL Method Mapping QTLs with MAPMAKER Usefulness of QTL Mapping Limitations of QTL Analysis Fine Mapping of QTL QTL Meta-Analysis
IMMUNOGENETICS Immunoglobulins Human Leukocyte Antigens Vaccines
GENETIC DISORDERS IN MAN Genetic Basis of Disorders Disorders Due to Mutations Diagnosis and Carrier Detection Somatic Cell Hybridization Treatment for Inherited Diseases Gene Therapy
ONCOGENES AND ANTIONCOGENES Retroviruses Contain Oncogenes Proto-Oncogenes src Oncogene Origin of Oncogenes Indentification of an Oncogene Fine Structure of an Oncogene Activation of Proto-Oncogenes A Model of Carcinogenesis Evidences Supporting Pall's Model Antioncogenes
SEX DETERMINATION, DOSAGE COMPENSATION AND SEX DIFFERENTIATION Sex-Determination Noncoding DNA as Hypothesis for Sex-Determination Dosage Compensation Sex Differentiation Events in Sex Determination Human Sex Anomalies
EPIGENETICS AND MORPHOGENETICS Epegenetic Patterns Mutations and Epimutations Cellular Transformation Chromosome Imprinting Epigenetic Defects and Ageing DNA Methylation in Plants Molecular Morphogenesis Common Coding Motifs Homeotic Genes in Flower Development
ORIGIN OF PROKARYOTIC AND EUKARYOTIC CELL Organic Evolution What is Life?
Theories of Origin of Life Mechanism of Origin of Life on Earth Evolution of Eukaryotes Theories on the Origin of Eukaryote Cells Evolution of Sexual Reproduction
PROCESS OF EVOLUTION Lamark's Theory of Evolutio Theory of Natural Selection Mutation Theory of Evolution Modern Synthetic Theory of Evolution
MOLECULAR EVOLUTION Biological Species Concept Genetics of Reproduction Isolation Genetic Distance An Era of Molecular Biology Evolutionarily Important Genes Molecular Evolutionary Clock Genome Organization and Evolution Selfish DNA Molecular Drive Proteome Cryptic Variation Establishment of New Patterns of Gene Control Epochs of Molecular Evolution
GENOMICS Assigning Function to a Gene Tools to Study Functional Genomics Potential Applications of Functional Genomics