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Doody's Review ServiceReviewer: Herbert L. Mathews, PhD (Loyola University Medical Center)
Description: The third edition of this book has been rewritten to focus on recent observations in immunology, with particular emphasis on intracellular and second messenger signaling.
Purpose: The purpose is to provide students with a more detailed understanding of immune system functions. The book is written for the student who already has a basic understanding of immunology and wants to further that understanding particularly in the areas of immune recognition, differentiation, cooperation, and effector mechanisms.
Audience: The book is most appropriate for students of biology and medicine who are interested in a more than basic understanding of immunology.
Features: As with the earlier editions, the line drawings are excellent and provide summarized and conceptualized information in a succinct format. Another feature that has the potential to be excellent is the occasional use of transmission electron micrographs. However, these micrographs suffer from their small size and from dark shading. This is not a major drawback in that the number of such micrographs is not large and does not detract significantly from the overall quality of the illustrations. The quality of the line drawings is exemplified in the chapter devoted to antigen processing and presentation in which the intracellular trafficking of MHC class I and 11 is depicted in a clear and concise fashion. Each chapter of the book is accompanied by extensive literature citations. These citations are alphabetized but not grouped with regard to content. As a consequence they are less accessible to students.
Assessment: This textbook is appropriate for its intended audience. It provides a very good bridge between introductory immunology for the beginning student and more advanced subject specific textbooks intended for immunologists interested in a particular specialty. The textbook is appropriate for purchase by students and librarians.