Advances in Molecular Toxicology [NOOK Book]

Overview

Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to...

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Advances in Molecular Toxicology

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Overview

Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.

Advances in Molecular Toxicology will report progress in all aspects of these rapidly evolving molecular aspects of toxicology with a view toward detailed elucidation of progress on the molecular level and on advances in technological approaches employed.

  • Cutting-edge reviews by leading workers in the discipline
  • In-depth dissection of molecular aspects of interest to a broad range of scientists, physicians and any student in the allied disciplines
  • Leading edge applications of technological innovations in chemistry, biochemistry and molecular medicine
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Editorial Reviews

Doody's Review Service
Reviewer: Udayan Apte, PhD, DABT (University of Kansas Medical Center)
Description: This book focuses on molecular mechanisms of toxicity (MOT) induced by several toxic chemicals relevant in the 21st century, including nanoparticles. The book also discusses use of newer methods for evaluation of MOT, such as proteomics.
Purpose: Understanding the molecular mechanisms behind the toxic action of chemicals is central to the discipline of toxicology. Overall, this book meets its objectives, but there are significant gaps in the discussion related to toxicodynamic response (produced by tissues in response to toxic chemical exposure).
Audience: It is intended for advanced practitioners of toxicology and should be an excellent resource for continuing education. The editor is relatively well published in the area of oxidative stress biology. The contributors are highly qualified in their respective fields.
Features: Most chapters are written from a chemistry standpoint and discuss existing paradigms and new theories. The chapters are concise and cover already known and new information with extensive referencing. However, most chapters have a significant lack of information about toxicodynamic response of tissues when they are exposed to these chemicals. Additional schematic representations would have helped novice readers to better understand material.
Assessment: This is a useful book for advanced practitioners of toxicology, mainly for continuing education and improving understanding of molecular mechanisms of toxicity induced by several environmentally and occupationally important chemicals.
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Product Details

  • ISBN-13: 9780444594020
  • Publisher: Elsevier Science
  • Publication date: 12/6/2012
  • Sold by: Barnes & Noble
  • Format: eBook
  • Pages: 320
  • File size: 5 MB

Table of Contents

1. Carbonyl/acrolein toxicity from a global cellular perspective - Philip C. Burcham

2. Heterocyclic arylamine carcinogens - Robert J. Turesky

3. Ni, Zn, Cu, Cd toxicity - Wojciech Bal

4. DNA radicals - Amanda Bryant-Friedrich

5. Duality in Nitric Oxide action - David Wink

6. Reactive Sulfur Species - Peter Nagy

7. Nano-silicate and other of nanoparticle toxicology - Aliasger K. Salem

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