Advances in Planar Lipid Bilayers and Liposomes

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Overview

Although the origin and the basic meaning of the terms "planar lipid bilayers" and "liposome" have not changed during the years, the present advances in the scientific, technological, biomedical and consumer product fields are remarkable. Ever since its launch the "Adances in Planar Lipid Bilayers and Liposomes’ (APLBL) has provided a global platform for a community of researchers having very broad scientific interests in theoretical, experimental and simulation studies on lipid and cell membrane micro and nanostructures. Ranging from artificial lipid membranes to cell membranes, controlled release of functional molecules, drug delivery to cancer cells, pharmaceutical formulations to food products, the applications are simply enormous. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.

Many ideas proposed in lipid nanoscience are frontier and futuristic, although some have immediate technological applications. The core scientific principles of lipid nanoscience and applications, however, are grounded in physics and chemistry. In last three decades the studies of polymorphism of lipid micro and nanostructures have gone through a major revolution concerning its understanding and evolution of new equilibrium and non-equilibrium structures of various length scales. Novel applications of the lipid micro and nanostructures are progressing rapidly among numerous disciplines. The APLBL book series gives a survey on recent theoretical as well as experimental results on lipid micro and nanonanostructures. In addition, the potentialuse of the basic knowledge in applications like clinically relevant diagnostic and therapeutic procedures, biotechnology, pharmaceutical engineering and food products is presented.

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Product Details

  • ISBN-13: 9780123812667
  • Publisher: Elsevier Science
  • Publication date: 11/1/2010
  • Pages: 296
  • Product dimensions: 6.20 (w) x 9.00 (h) x 1.40 (d)

Meet the Author

Aleš Iglic received his B.Sc. and Ph.D. degrees in physics and M.Sc. degree in biophysics from the Department of Physics, and the Ph.D. degree in electrical engineering from the Faculty of Electrical Engineering, all from the University of Ljubljana. He is a Full Professor and the Head of Laboratory of Biophysics of the Faculty of Electrical Engineering at University of Ljubljana. His main research interests are in electrostatics, mechanics and statistical physics of lipid nanostructures and biological membranes. He is devoted to higher education, basic research in biophysics and close contacts to clinical practice. Prof. Iglic was visiting scientist and professor at Åbo Akademi University in Turku (Finland), Friedrich Schiller University in Jena (Germany) and Czech Technical University in Prague (Czech Republic). He established collaborations with researchers from different universities across the Europe, USA and India and was supervisor of many M.Sc. , Ph.D. and postdoctoral students from Slovenia, Czech Republic, Poland, Iran, Bulgaria, Germany, India and Israel. Since 2009 is the editor of Elsevier book series »Advances in Planar Lipid Bilayers and Liposomes« (APLBL).

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Table of Contents

1 Lipid microvesicles : on the four decades of liposome research 1
2 Surface properties of liposomes depending on their composition 49
3 Interactions of Al and related metals with membrane phospholipids : consequences on membrane physical properties 79
4 Interaction of plant polyphenols with liposomes 107
5 Cationic liposomes as transmembrane carriers of nucleic acids 135
6 Molecular interactions between lipid and its related substances in bilayer membranes 191
7 Cell-mimicking supramolecular assemblies based on polydiacetylene lipids : recent development as "smart" materials for colorimetric and electrochemical biosensing devices 229
8 Budding of liposomes - role of intrinsic shape of membrane constituents 253
9 Electrical properties of aqueous liposome suspensions 281
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