Advances in the Management of Testosterone Deficiency

Advances in the Management of Testosterone Deficiency

by T. Hugh Jones
     
 

A concise review of recent scientific and clinical research Testosterone has an important influence on major organ systems and tissues, including brain, metabolism, cardiovascular as well as musculoskeletal and immune systems. Covering many clinical areas, this book pays particular attention to the diagnosis and management of hypogonadism, discussing current

Overview

A concise review of recent scientific and clinical research Testosterone has an important influence on major organ systems and tissues, including brain, metabolism, cardiovascular as well as musculoskeletal and immune systems. Covering many clinical areas, this book pays particular attention to the diagnosis and management of hypogonadism, discussing current guidelines, biochemical assessment, new options in testosterone replacement therapy and long-term monitoring of treated men. Furthermore the role of testosterone deficiency in aging, obesity, muscle function and frailty and erectile dysfunction is covered. Recent evidence for the role of testosterone in the pathogenesis of chronic diseases such as diabetes, cardiovascular disease and osteoporosis is reported. New developments in the potential treatment of these clinical conditions are also presented. Primarily of interest to endocrinologists, urologists, andrologists and sexologists, the range of topics covered is also relevant to primary care physicians, gerontologists, diabetologists and cardiologists.

Editorial Reviews

Doody's Review Service
Reviewer: Ronald N. Cohen, MD (University of Chicago Medical Center)
Description: This book addresses an important issue in endocrinology, the use of testosterone as replacement therapy in hypogonadism. There has been much controversy in the field, in both the definition of hypogonadism itself, as well as the indications, risks, and benefits of testosterone therapy. This multiauthored book tackles these important questions.
Purpose: The purpose is to guide clinicians in the use of testosterone replacement treatments, their respective advantages and disadvantages, and their indications for use. These are important objectives, since options for testosterone replacement therapies have increased in recent years, and there has been a variety of controversies surrounding the potential risks and benefits of such therapies.
Audience: Clinicians who treat men with hypogonadism, including internists, endocrinologists, and urologists, are the intended audience. The authors are all experts in this field.
Features: The book starts with a discussion of hypogonadism, including issues with the definition of this disorder. An explanation of the laboratory measurement of testosterone, free testosterone, and bioactive testosterone follows. After a discussion of CAG repeats on the function of the androgen receptor, the bulk of the book covers various metabolic and other issues in testosterone deficiency and treatment, including obesity, metabolic syndrome, coronary artery disease, erectile dysfunction, osteoporosis, frailty and cognition, and congestive heart failure. The book ends with an exploration of testosterone and prostate safety, with the interesting idea that exogenous testosterone may not increase intra-prostatic concentrations of the hormone.
Assessment: This is a very useful book to learn how testosterone deficiency may impact on a variety of metabolic and other processes, as well as the potential benefits of replacement therapy. Although the various authors do mention the limited studies of both risks and benefits of testosterone therapy, the emphasis in this book is more on possible benefits of treatment than on potential concerns.

Product Details

ISBN-13:
9783805586221
Publisher:
Karger, S. Inc.
Publication date:
08/31/2008
Series:
Frontiers of Hormone Research Series
Pages:
208

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