Advances in Transition-Metal Mediated Heterocyclic Synthesis

by Daniel Sole, Israel Fernandez

Overview

Advances in Transition-Metal Mediated Heterocyclic Synthesis provides an overview of recent catalytic reactions involving transition metals to produce heterocyclic compounds. The book is organized according to the type of transformation used to achieve the synthesis of the heterocyclic systems (mainly aza- and oxa-heterocycles). As such, it covers recent applications on the synthesis of heterocycles, also describing the details of the novel transformations in a didactic manner to motivate readers in search of new catalytic processes. The editors have included state-of-the-art strategies, including transition-metal reactions involving unsaturated systems (reactions of allenes, new gold(I)-catalyzed reactions, and Prins reaction).

Chapters highlight the versatility of organopalladium chemistry dealing with carbonylative transformations, C-H activation reactions, coupling processes, and the control of the ambiphilic character of organopalladium species. Finally, the book discusses new reactions leading to heterocycles based on C-H activation processes catalyzed by other metals (Rh, Ru, Co).

Written by an outstanding team of authors who are leading experts in organometallic chemistry and organic synthesis, this book is a valuable resource not only for chemists mainly focused on synthesis, but also for those interested in reaction mechanisms involving transition metals.

Product Details

ISBN-13:	9780128116517
Publisher:	Elsevier Science
Publication date:	05/19/2018
Pages:	366
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

Dr. Daniel Sole is a Professor in the Department of Organic Chemistry at the University of Barcelona, Spain. He is an expert in in the development of transition metal—-catalyzed transformations towards the synthesis of new species (especially heterocyclic compounds), as well as in the study of the reaction mechanisms and bonding situation of key intermediates involved in these transformations. He has published several papers on palladium-catalyzed C–H activation, a-arylation, and palladium-catalyzed nucleophilic addition reactions

Dr. Israel Fernandez (Madrid, 1977) studied Chemistry at the Universidad Complutense de Madrid (UCM). After obtaining his PhD degree (with honors) under the supervision of Prof. M. A. Sierra, he joined the Theoretical and Computational Chemistry group of Prof. G. Frenking at the Philipps-Universität Marburg as a postdoctoral researcher. He received several awards including the Julián Sanz del Río award and the Barluenga's medal. At present, he is Profesor Titular at the UCM. His current research is focused on both the bonding situation of organic and organometallic compounds and their reactivity.

Table of Contents

1. Metal-mediated synthesis of non-aromatic oxacycles from allenols
Pedro Almendros and Benito Alcaide
2. Intramolecular diamination of alkenes
Kilian Muniz
3. Synthesis of heterocycles by palladium-catalyzed carbonylative reactions
Bartolo Gabriele
4. Synthesis of heterocyclic compounds based on transition-metal-catalyzed carbene coupling reactions
Jianbo Wang
5. Synthesis of heterocycles with iron salts as sustainable metal catalysts
Juan I. Padrón
6. Allene aziridinations as a tool for the synthesis of complex amines
Jennifer M. Schomaker
7. Zinc-mediated synthesis of heterocycles
Ruben Vicente
8. Controlling selectivities in palladium-catalyzed cyclization reactions leading to heterocycles: From ambiphilic reactions of arylpalladium species to carbene
Israel Fernández and Daniel Solé

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From the Publisher

A collection of state-of-the-art reactions and catalysts used to synthesize heterocyclic compounds