Advances in Virus Research / Edition 1

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This latest volume in the Advances in Virus Research series presents articles on topics such as the role of lipid rafts in virus assembly and budding; novel vaccine strategies; treatment of arenavirus infections; the evaluation of drug resistance in HIV infection; perspectives on polydnavirus origin and evolution; bateriophage 29 DNA packaging; the potential of plant viral vectors and transgenic plants for subunit vaccine production; and the interaction of orthopoxviruses with interferon-treated cultured cells. This timely and informative compilation of articles will be of interest to researchers in the fields of virology, immunology, microbiology, and plant science.

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Editorial Reviews

Doody's Review Service
Reviewer: Jose Romero, MD (Creighton University Medical Center)
Description: Volumes 53 and 54 of Advances in Virus Research contain up-to-date reviews of topics related to virology, written and edited by experts in each of the areas covered. Together they contain 27 well written articles.
Purpose: These volumes are written to provide the reader with reviews on topics related to virology.
Audience: The reviews contained in these two volumes will be of value and interest to graduate students, physicians, veterinarians, and investigators interested in familiarizing or updating themselves in the subjects covered.
Features: Volume 53 contains two "special sections." In the first contributors consider the current status and impact of viral diseases on the developing world. There are six reviews in which they deal with three major human diseases (yellow fever, dengue, and human deficiency virus), two major diseases of livestock (rinderpest, foot and mouth disease), and viral diseases of importance to horticulture. In the second section they provide reviews of the use of reverse genetics for the study of different groups of RNA viruses. Each review in this section is focused on how the different viral replication strategies have influenced the reverse genetics approach taken. The contributors cover four positive stranded viruses (flavivirus, picornavirus, nodavirus, coronavirus), three negative stranded viruses (rhabdovirus, paramyxovirus), double stranded viruses (dsRNA viruses of higher organisms) and the practical application of reverse genetics for control of viral plant infections. Volume 54 contains six reviews and a "special section" on respiratory viruses (influenza viruses, paramyxoviruses, respiratory syncytial virus, rhinoviruses). The contributors cover exceptionally timely topics such as influenza vaccines and influenza neuraminidase inhibitors.
Assessment: The editors of Volumes 53 and 54 of Advances in Virus Research continue the long tradition of authoritative, well-written, current reviews on selected topics related to virology. Both volumes have a wealth of up-to-date information. All of the reviews contain excellent reference sections for those wishing more detailed information.
From the Publisher
"This well known to virologists. It is a valuable aid in maintaining an overview of various facets of the rapidly expanding fields of virology...Timely, informative, and useful to the student, teacher, and research scientist."
"A mandatory purchase for all types of comprehensive libraries, both public and university, as well as for those interested in or doing research in the field of virology."
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Product Details

  • ISBN-13: 9780120398539
  • Publisher: Elsevier Science
  • Publication date: 10/11/1999
  • Series: Advances in Virus Research Series
  • Edition number: 1
  • Pages: 399
  • Product dimensions: 6.34 (w) x 9.35 (h) x 0.88 (d)

Meet the Author

Frederick A. Murphy, DVM, PhD, is professor, Department of Pathology, University of Texas Medical Branch (UTMB), Galveston. He holds a BS and DVM from Cornell University and a PhD from the University of California, Davis (UC Davis). Formerly he was dean and distinguished professor, School of Veterinary Medicine, and distinguished professor, School of Medicine, UC Davis. Before that he served as director of the National Center for Infectious Diseases, and director of the Division of Viral and Rickettsial Diseases, Centers for Disease Control, Atlanta. He is a member of the Institute of Medicine of the U.S. National Academy of Sciences and is a member of the German National Academy of Sciences and the Belgian Royal Academy of Medicine. He holds an honorary Doctor of Medicine and Surgery from the University of Turku, Finland; an honorary Doctor of Science from the University of Guelph, Canada; an honorary Doctor of Veterinary Medicine from the University of London, United Kingdom; an honorary Doctor of Science from University College Dublin, Ireland; the Presidential Rank Award of the U.S. Government; the PennVet World Leadership Award from the University of Pennsylvania, and the Distinguished Microbiologist Award from the American College of Veterinary Microbiologists. At UTMB, he is a member of the Institute for Human Infections and Immunity, Center for Biodefense and Emerging Infectious Diseases, Galveston National Laboratory, and McLaughlin Endowment for Infection and Immunity. His professional interests include the pathology and epidemiology of highly pathogenic viruses/viral diseases: rabies and the rabies-like viruses, arboviruses, hemorrhagic fever viruses, and other neurotropic viruses. He has been a leader in advancing the concepts of “new and emerging infectious diseases” and “new and emerging zoonoses” and “the threat posed by bioterrorism.” Most recently, he has been working on Internet resources on the history of virology: “The Foundations of Virology” at

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Table of Contents

DNA Vaccines for Viral Infections: Basic Studies and Applications, H.L. Robinson and T.M. Pertmer.
SV40 Large T Antigen Functions in DNA Replication and Transformation, D.T. Simmons.
Viral and Cellular mRNA Capping: Past and Prospects, Y. Furuichi and A.J. Shatkin.
Mechanism of Genome Transcription in Segmented dsRNA Viruses, J.A. Lawton, M.K. Estes, and B.V. Venkataram Prasad.
Structures and Mechanisms in Flavivirus Fusion, F.X. Heinz and S.L. Allison.
Avsunviroidae Family: Viroids Containing Hammerhead Ribozymes, R. Flores, J.-A. Daròs, and C. Harnández.
Virus Resistance Mediated by Ribosome Inactivating Proteins, P. Wang and N.E. Turner.
Groundnut Rosette Disease Virus Complex: Biology and Molecular Biology, M.E. Taliansky, D.J. Robinson, and A.F. Murant.
Special Section: Virus Vectors for Gene Therapy:
Guest Editor J.C. Glorioiso.
Perspectives on Viral Vector Design and Applications, J.C. Glorioiso.
Replication-Competent Herpes Simplex Viral Vectors for Cancer Therapy, N.S. Markovitz and B. Roizman.
Herpes Simplex Virus Type 1-Based Amplicon Vector Systems, C. Fraefel, D.R. Jacoby, and X.O. Breakfield.
Epstein-Barr Virus Vectors for Gene Therapy, S. Komaki and J.-M. H. Vos.
Cytomegalovirus Bacterial Artificial Chromosomes: A New Herpesvirus Vector Approach, M. Messerle, G. Hahn, W. Brune, and U.H. Koszinowski.
Adenovirus Vectors for Human Gene Therapy, M.M. Hitt and F.L. Graham.
Adeno-Associated Virus Vector-Mediated Gene Transfer to Somatic Cells in the Central Nervous System, R.L. Klein, R.J. Mandel, and N. Muzycka.
Production of Recombinant Adeno-Associated Virus, G.-P. Gao, J.W. Wilson, and N.A. Wivel.
Retroviral Vectors, S.H. Kim, S. Kim, and P.D. Robbins.
Alphavirus Expression Vectors, S. Schlesinger.
Transfectant Influenza Viruses As Antigen Delivery Vectors, A. García-Sastre.
Lentiviral Vectors, L. Naldini and I.M. Verma.

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