Advancing Nuclear Medicine Through Innovation

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Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized.

Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

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Product Details

  • ISBN-13: 9780309110679
  • Publisher: National Academies Press
  • Publication date: 9/20/2007
  • Pages: 176
  • Product dimensions: 6.04 (w) x 9.00 (h) x 0.42 (d)

Table of Contents

Summary     1
Introduction     10
Strategy to Address the Study Charge     14
Report Roadmap     15
Nuclear Medicine     17
Significant Discoveries     22
Frontiers in Nuclear Medicine     23
Complexities of Nuclear Medicine Practice and Research     38
Conclusion     42
Nuclear Medicine Imaging in Diagnosis and Treatment     43
Background     43
Current State of Nuclear Medicine Imaging and Emerging Priorities     44
Impediments to Progress and Current and Future Needs     56
Targeted Radionuclide Therapy     59
Background     60
Significant Discoveries     65
Current State of the Field and Emerging Priorities     66
Current Impediments to Full Implementation of Targeted Radiopharmaceutical Therapeutics     72
Recommendations     73
Conclusions     74
Availability of Radionuclides for Nuclear Medicine Research     75
Background     75
Significant Discoveries     76
Current State of Radionuclide Availability in the United States     80
Current and Future Needs     83
Recommendations     87
Radiotracer and Radiopharmaceutical Chemistry     89
Background     89
Significant Discoveries     90
Current State of the Field and Emerging Priorities     93
Current Needs and Impediments     101
Recommendations     102
Instrumentation and Computational Sciences     104
Background     104
Significant Discoveries     107
Current State of the Field and Emerging Priorities     111
Future Needs     114
Findings     116
Recommendations     117
Education and Training of Nuclear Medicine Personnel     118
Background     118
Current Status of the Workforce     119
Findings     129
Recommendations     130
References     131
Information-Gathering Sessions     141
Glossary and Acronyms     146
Commercially Available Radiopharmaceuticals     151
Biographical Sketches of Committee Members     155
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