Ageing Vulnerability: Causes and Interventions - No. 235 / Edition 1

Hardcover (Print)
Buy New
Buy New from BN.com
$212.00
Used and New from Other Sellers
Used and New from Other Sellers
from $16.00
Usually ships in 1-2 business days
(Save 92%)
Other sellers (Hardcover)
  • All (9) from $16.00   
  • New (5) from $168.67   
  • Used (4) from $16.00   

Overview

Aging at individual and population levels presents one of the greatest challenges to humankind as we begin the 21st century. Throughout the world, older adults are the fasts growing population group. Aging is associated with an increased risk for development of chronic diseases that contribute to morbidity and mortality.
Read More Show Less

Product Details

  • ISBN-13: 9780471494386
  • Publisher: Wiley
  • Publication date: 3/28/2001
  • Series: Novartis Foundation Symposia Series , #204
  • Edition number: 1
  • Pages: 292
  • Product dimensions: 6.22 (w) x 9.35 (h) x 0.73 (d)

Meet the Author

Iminosugars may be regarded as glycomimetics, alkaloids, natural products or as potential drugs. This book should therefore interest academic and industrial researchers in various areas such as organic synthesis, carbohydrate chemistry, medicinal chemistry, biochemistry, biotechnology, biology and medical sciences.
Read More Show Less

Table of Contents

Introduction 1
The priority of basic research on ageing vulnerability in a comprehensive research agenda on ageing for the 21st century 4
Do alterations in glutathione and iron levels contribute to pathology associated with Parkinson's disease? 11
Specific metal-catalysed protein oxidation reactions in chronic degenerative disorders of ageing: focus on Alzheimer's disease and age-related cataracts 26
Multiple substrates of late-onset dementia: implications for brain protection 49
Ageing of murine small intestinal stem cells 66
Haematopoietic stem cell ageing 85
Identification of genes involved in cell senescence and immortalization: potential implications for tissue ageing 105
Ageing and cancer: the telomere and telomerase connection 116
Ageing and the immune system 130
Mechanisms of age-related bone loss 150
The old heart: operating on the edge 172
Pharmaceutical intervention of advanced glycation endproducts 202
The anti-ageing action of dietary restriction 221
Mitochondrial DNA mutations in disease and ageing 234
A mitochondrial paradigm for degenerative diseases and ageing 247
Index of contributors 273
Subject index 275
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)