AIDS in Africa / Edition 1

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Overview

This comprehensive reference book addresses the unique challenges facing many African nations as poor infrastructure and economics continue to obstruct access to advanced treatments and AIDS care training. It takes into account the context of settings with limited resources. Information on how to best utilize existing resources and prioritize scaling-up of infrastructure is a critical aspect of this book for those working in HIV/AIDS-related fields in Africa.

This book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: John A. Robinson, MD (Loyola University Stritch School of Medicine)
Description: This book is written by specialists from three continents. Some of the authors are authorities in HIV; others may be well known throughout Africa and in some parts of the WHO community, but they do not have a high visibilty in the U.S. The format is traditional without any unique features.
Purpose: The purpose is apparently (although it is only implied) to highlight unusual or unique features of HIV in Africa.
Audience: The intended audience is infectious disease specialists and some public health personnel.
Features: This book has more than the usual amount of flaws encountered in a multiauthored book. It is not current, with most of its references dating to 1991 or earlier. The quality of the chapters is very uneven; strikingly, almost a third of the book is devoted to HIV knowledge that is not unique to Africa. Put another way, the book is overblown and could have been written in a much more concise fashion with a secondary benefit of reducing its extraordinary price of $160 to something in a morereasonable range. Its scientific content is immediately tarnished by the almost inevitable politicized introduction by a journalist; however, some chapters are quite valuable, especially chapter 5 and most in chapters in section 2. Conversely, there are several very poor chapters, especially the one in which the author provides five good reasons why estimates and projections of HIV in sub-Sahara Africa are almost impossible to make and then proceeds to write 15 pages making projections!Finally, chapter 27 on the economic importance of AIDS is an extraordinary exercise in fantasy. The economics of Africa, per se, are not understood in the least, but the author attempts to relate that non-knowledge to the effects of a disease that is very difficult to predict.
Assessment: Some chapters in this book will be valuable for readers interested in the uniqueness of African AIDS, but other than those, the book is not very useful.
John A. Robinson
This book is written by specialists from three continents. Some of the authors are authorities in HIV; others may be well known throughout Africa and in some parts of the WHO community, but they do not have a high visibilty in the U.S. The format is traditional without any unique features. The purpose is apparently (although it is only implied) to highlight unusual or unique features of HIV in Africa. The intended audience is infectious disease specialists and some public health personnel. This book has more than the usual amount of flaws encountered in a multiauthored book. It is not current, with most of its references dating to 1991 or earlier. The quality of the chapters is very uneven; strikingly, almost a third of the book is devoted to HIV knowledge that is not unique to Africa. Put another way, the book is overblown and could have been written in a much more concise fashion with a secondary benefit of reducing its extraordinary price of $160 to something in a morereasonable range. Its scientific content is immediately tarnished by the almost inevitable politicized introduction by a journalist; however, some chapters are quite valuable, especially chapter 5 and most in chapters in section 2. Conversely, there are several very poor chapters, especially the one in which the author provides five good reasons why estimates and projections of HIV in sub-Sahara Africa are almost impossible to make and then proceeds to write 15 pages making projections!Finally, chapter 27 on the economic importance of AIDS is an extraordinary exercise in fantasy. The economics of Africa, per se, are not understood in the least, but the author attempts to relate that non-knowledge to the effects of adisease that is very difficult to predict. Some chapters in this book will be valuable for readers interested in the uniqueness of African AIDS, but other than those, the book is not very useful.
From The Critics
Specialists in several medical fields from Africa and elsewhere update the reference to reflect changing conditions and prospects during the eight years since the first edition. Among the intervening events are millions of deaths and new infections so that AIDS has now surpassed the bubonic plague of the 14th century as the most deadly epidemic, a shift of some attention from Europe and the US to Africa, the emergence and in some cases availability of drugs effective in treatment, and renewed commitments by international agencies and foundations. The information is intended to be useful to those engaged in the struggle and a call to arms for others to join. Annotation c. Book News, Inc., Portland, OR
Booknews
An expert detailing of the primary biomedical, epidemiologic, and human realities that characterize the first decade of the AIDS epidemic in Africa. The volume's 33 chapters are organized into six sections: biology and etiology, epidemiology, clinical manifestations and treatments, preventive strategies, social and economic impact, and geographic variations. Annotation c. Book News, Inc., Portland, OR (booknews.com)

2 Stars from Doody
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Product Details

  • ISBN-13: 9780781701105
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 1/1/1994
  • Edition description: Older Edition
  • Edition number: 1
  • Pages: 728

Table of Contents

I Pathogenesis
1 Introduction: The Etiology of AIDS 1
2 The Molecular Virology of HIV-1 11
3 Immunopathogenesis of AIDS 34
4 Effect of Genetic Variation on HIV Transmission and Progression to AIDS 52
5 Biology of Human Immunodeficiency Virus Type 2 HIV-2 74
6 Simian Immunodeficiency Viruses and the Origin of HIVs
II Detection and Monitoring of HIV Infection and Disease
7 Serodiagnosis of HIV Infection 121
8 Molecular Diagnosis of HIV Infection 138
9 Monitoring HIV-1 Subtype Distribution 158
10 Monitoring Viral Load 173
11 Monitoring Immune Function 185
III Epidemiology
12 The Epidemiology of HIV and AIDS 200
13 Transmission of HIV 217
14 Role of Sexually Transmitted Diseases in HIV-Transmission 231
15 Mother-to-Child Transmission of HIV 251
16 HIV-1 Subtypes and Recombinants 263
17 Current Estimates and Projections for the Epidemic 281
IV Clinical Spectrum and Treatment of HIV-Related Diseases
18 Clinical Diagnosis of AIDS and HIV-Related Diseases 297
19 Antiretroviral Therapy in Resource-Limited Settings 322
20 HIV-1 Drug Resistance 345
21 Opportunistic Infections 355
22 Tuberculosis 373
23 HIV Infection and Cancer 386
24 Challenges and Opportunities for Nurses 405
25 Home-Based Care 411
26 Nutrition and HIV Infection 419
27 Access to HIV and AIDS Care 436
V Pediatric HIV Infection and Disease
28 Diagnosis of Pediatric HIV Infection 458
29 Treatment of HIV in Children Using Antiretroviral Drugs 469
30 Pediatric Opportunistic Infections 480
VI Preventions of HIV Infection
31 Male Condoms and Circumcision 498
32 Female Condoms and Microbicides 506
33 Behavioral Change: Goals and Means 514
34 Voluntary Counseling and Testing 527
35 Prevention of Perinatal Transmission of HIV 539
36 Prevention of Breast Milk Transmission of HIV: Balancing the Benefits and the Risks 560
37 Postexposure Prophylaxis for Occupational Exposure and Sexual Assault 571
VII Vaccine Development
38 The Need for a Vaccine 584
39 HIV Vaccines: Design and Development 594
40 HIV-1 Vaccine Testing, Trial Design, and Ethics 612
VIII Impact and Response
41 Regional Variations in the African Epidemics 631
42 Human Rights and HIV/AIDS 641
43 Gender and HIV/AIDS 654
44 The Orphan Crisis 664
45 The Economics of AIDS in Africa 676
46 International Cooperation and Mobilization 695
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