BN.com Gift Guide

The Amide Linkage: Structural Significance in Chemistry, Biochemistry, and Materials Science / Edition 1

Hardcover (Print)
Buy New
Buy New from BN.com
$278.18
Used and New from Other Sellers
Used and New from Other Sellers
from $83.00
Usually ships in 1-2 business days
(Save 75%)
Other sellers (Hardcover)
  • All (5) from $83.00   
  • New (5) from $83.00   

Overview

One of the most fundamental and widespread chemical bonds in nature, the amide linkage underlies the properties of a vast array of organic molecules, polymers, and materials, including peptides and proteins. This new work covers state-of-the-art research in amide linkage. It features contributions by eminent chemists and biochemists worldwide who discuss structure and bonding principles of the amide linkage as well as applications.
Read More Show Less

Editorial Reviews

From the Publisher
"It makes extremely interesting reading" (Angewandte Chemie, International Edition 19 November 2001)

"...will have a longer than average shelf life..."(European Peptide Society Newsletter, 1 January 2003)

"...excellent chapters and provides plenty of useful background information on amide structure." (Angewandte Chemie, International Edition, Vol. 42, 2003)

Booknews
Meant to complement Zabicky's 1970 by being broader in scope and placing less emphasis on the synthesis and reactions of amides, the 18 studies present many aspects of the structure, bonding, and dynamics of amides and their influences on chemical, physical, biological, and material properties. They focus on structural, energetics, and bonding perspective with a view to understanding physical and chemical properties. They also provide background and context for non-experts before sounding the depths in a particular area. Their topics include the electron density distribution of amides and related compounds, the properties and the role of distortion of the amide linkage as a ligand, the thermochemistry, beta-lactams as cyclic amides of distinction, sterically hindered twisted amides, the three-dimensional design of enzyme inhibitors with heterocyclic amide bond mimics, head-to-tail cyclic peptides and cyclic peptide libraries, and the role of the peptide bond in protein structure and folding. The subtitle on the cover differs from other versions by reading Structural Significance in Chemistry, Biochemistry, and Materials Science. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Read More Show Less

Product Details

  • ISBN-13: 9780471358930
  • Publisher: Wiley
  • Publication date: 1/28/2000
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 672
  • Product dimensions: 6.38 (w) x 9.65 (h) x 1.48 (d)

Meet the Author

ARTHUR GREENBERG, PhD, is Professor in the Department of Chemistry at the University of New Hampshire.

CURT M. BRENEMAN, PhD, is Professor in the Department of Chemistry at Rensselaer Polytechnic Institute.

JOEL F. LIEBMAN, PhD, is Professor in the Department of Chemistry and Biochemistry at the University of Maryland, Baltimore County.

Read More Show Less

Table of Contents

Preface
Contributors
1 The Electron Density Distribution of Amides and Related Compounds 1
2 Origin of the Amide Rotational Barrier 33
3 The Amide Linkage as a Ligand - Its Properties and the Role of Distortion 47
4 Studies in Amide Hydrolysis: The Acid, Base, and Water Reactions 85
5 The Thermochemistry of Amides 115
6 Stereospecificity in the [alpha]-Lactam (Aziridinone) Synthon 137
7 [beta]-Lactams: Cyclic Amides of Distinction 157
8 Sterically Hindered Twisted Amides 215
9 Photoelectron Spectroscopy of Amides and Lactams 247
10 The Role of Amides in the Noncovalent Synthesis of Supramolecular Structures in Solution, at Interfaces, and in Solids 291
11 [beta]-Lactam Antibacterial Agents: Computational Chemistry Investigations 337
12 Three-Dimensional Design of Enzyme Inhibitors with Heterocyclic Amide Bond Mimics 377
13 Ab Initio Conformational Analysis of Protein Subunits: A Case Study of the Serine Diamide Model 409
14 Gas-Phase Ion Chemistry of Amides, Peptides, and Proteins 463
15 [beta]-Sheet Interactions Between Proteins 495
16 Head-to-Tall Cyclic Peptides and Cyclic Peptide Libraries 519
17 From Crystal Structures of Oligopeptides to Protein Folding: The Importance of Peptide Bond-Side Chain Hyperconjugation 565
18 Role of the Peptide Bond in Protein Structure and Folding 599
Index 627
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)