Amino Acid Derivatives

Hardcover (Print)
Buy New
Buy New from BN.com
$213.75
Used and New from Other Sellers
Used and New from Other Sellers
from $106.01
Usually ships in 1-2 business days
(Save 52%)
Other sellers (Hardcover)
  • All (5) from $106.01   
  • New (3) from $213.56   
  • Used (2) from $106.01   

More About This Textbook

Overview

Amino acids are increasingly becoming the first compound that chemists turn to when planning a synthesis leading to a homochiral target. Much of this activity is centered around peptide synthesis, however there is a very wide and demanding range of chemistry that describes the synthesis of derivatives of the *a-amino acids and some uses of those derivatives that do not involve peptides. This book supports several of these areas of chemistry and describes representative methods for introducing substituents at the amino group, modifying carboxy groups, and modifying the side-chains of some common *a-amino acids. There is little discussion of peptide synthesis, although some of the basic protocols in the book are relevant to the modification of amino acids for this purpose. Instead, the authors here focus on the rapidly growing applications of amino acids in many other areas of modern organic synthesis. Any synthetic work carried out by those in the fields of organic and medicinal chemistry will be supported by the detailed practical protocols and background information provided in this book.

Read More Show Less

Product Details

  • ISBN-13: 9780198558538
  • Publisher: Oxford University Press, USA
  • Publication date: 1/28/2002
  • Series: Practical Approach in Chemistry Series
  • Pages: 288
  • Product dimensions: 6.30 (w) x 9.30 (h) x 0.80 (d)

Table of Contents

Preface
1. Introduction, Graham C. Barrett
2. Acylation and alkoxycarbonylation of the amino group, Graham C. Barrett
3. Thioacylatin of the amino group of amino acids, Graham C. Barrett
4. Mono- and Di-alkylatin of the amino group, Graham C. Barrett
5. Reactions at the carboxy group of an amino acid: Amino acid salts, Graham C. Barrett
6. Reactions at the carboxy group of an amino acid: Esterification of amino acids, Graham C.Barrett
7. Carboxy group modifications; synthesis of a homochiral ketone derived from L-tryptophan, K.J. Merchant
8. Synthons derived from Aspartic and glutamic acids, M.G. Moloney
9. Benzophenone schiff bases of a-Amino acid esters as electrophiles. Addition of grignard reagents and alkly-lithiums to produce threo-amino alcohols and aminopolyols, R.J. Polt
10. Synthetic uses of serine, threonine and cysteine, P. Meffre et al
11. Synthetic uses of methionine, P. Meffre et al
12. Metal-mediated modification of the side-chains of a-amino acids, G.T. Crisp
13. Diastereocontrolled functionalisation of enantiomerically pure 5-phenyl-1, 4-Oxazin-2-ones by azomethine ylid generation and trapping, A.S. Anslow et al
14. Reductive modifications of the carboxy-group, Graham C. Barrett
15. Reactions at the a-Carbon Atom of a-Amino acid derivatives
16. Modifications of the Aryl substitutents of a- and beta-aryl a-amino acids
17. Isolation and chromatographic purification of reaction products from amino acids, I.A. O'Neil
Index

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)