Aminopeptidases

Aminopeptidases

by Allen Taylor
     
 

This book summarizes recently gathered information regarding the aminopeptidases. Nomenclature, distributions in the plant and animal kingdoms, structural and compositional information, mechanistic studies, homologies, physiological, medical and industrial uses, and molecular genetics of aminopeptidases are described.See more details below

Overview

This book summarizes recently gathered information regarding the aminopeptidases. Nomenclature, distributions in the plant and animal kingdoms, structural and compositional information, mechanistic studies, homologies, physiological, medical and industrial uses, and molecular genetics of aminopeptidases are described.

Editorial Reviews

Howard H. Sky-Peck
This is an excellent up-to-date review of the group of enzymes known as aminopeptidases. The purpose is to acquaint and bring up-to-date bioscientists on the complexity and diversity of this family of enzymes. The intended audience includes teachers, researchers, and graduate students in the field of biochemistry. Aminopeptidases catalyze the cleavage of amino acids from the amino-terminus of protein or peptide substrates. They are widely distributed throughout the animal and plant kingdoms. They are found in many subcellular organelles, in cytoplasm, and as membrane components. Mutation of several aminopeptidases has been found to be lethal to cells, clearly indicating essential cellular functions for these enzymes. Several aminopeptidase structures and functions have been included in this text. Mechanistic information has progressed significantly, and many functions, including dual functions for these enzymes, have been elucidated. Nomenclature, biological uses, occurrence in the natural kingdoms, and regulation of expression of the enzymes are considered. An in-depth consideration of structure and mechanistic features also includes the role of metal ions. This is an excellent detailed review of a family of enzymes that are widely distributed throughout nature. These enzymes are very important in genetics and disease. Not only is this book a must for science libraries, it should be a text for teaching courses in graduate biochemistry.
Reviewer: Howard H. Sky-Peck, MD, PhD, FRSM (Rush Medical College of Rush University)
Description: This is an excellent up-to-date review of the group of enzymes known as aminopeptidases.
Purpose: The purpose is to acquaint and bring up-to-date bioscientists on the complexity and diversity of this family of enzymes.
Audience: The intended audience includes teachers, researchers, and graduate students in the field of biochemistry.
Features: Aminopeptidases catalyze the cleavage of amino acids from the amino-terminus of protein or peptide substrates. They are widely distributed throughout the animal and plant kingdoms. They are found in many subcellular organelles, in cytoplasm, and as membrane components. Mutation of several aminopeptidases has been found to be lethal to cells, clearly indicating essential cellular functions for these enzymes. Several aminopeptidase structures and functions have been included in this text. Mechanistic information has progressed significantly, and many functions, including dual functions for these enzymes, have been elucidated. Nomenclature, biological uses, occurrence in the natural kingdoms, and regulation of expression of the enzymes are considered. An in-depth consideration of structure and mechanistic features also includes the role of metal ions.
Assessment: This is an excellent detailed review of a family of enzymes that are widely distributed throughout nature. These enzymes are very important in genetics and disease. Not only is this book a must for science libraries, it should be a text for teaching courses in graduate biochemistry.

Read More

Product Details

ISBN-13:
9783662216057
Publisher:
Springer Berlin Heidelberg
Publication date:
11/28/2013
Series:
Molecular Biology Intelligence Unit Series
Edition description:
Softcover reprint of the original 1st ed. 1996
Pages:
220
Product dimensions:
7.01(w) x 10.00(h) x 0.50(d)

Related Subjects

Customer Reviews

Average Review:

Write a Review

and post it to your social network

     

Most Helpful Customer Reviews

See all customer reviews >