Amphibian Metamorphosis: From Morphology to Molecular Biology / Edition 1

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0471244759 Premium Publisher Direct Books are Like New or Brand New books direct from the publisher sometimes at a discount. Multiple copies are usually available. These books ... are not available for expedited shipping and may take up to 14 business days to receive. Read more Show Less

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Overview

In an age when advanced molecular and genetic tools allow studies in v arious systems, amphibian metamorphosis still offers perhaps the most accessible model for the study of postembryonic organogenesis and mech anisms of hormonal regulation during vertebrate development. Amphibian Metamorphosis: From Morphology to Molecular Biology integrates findin gs from the most recent research with earlier observations, providing molecular and mechanistic insights into the signal transduction pathwa ys underlying tissue-specific transformations during metamorphosis.

Metamorphosis is a first rate example of post embryonic development, with research into the area integrating molecular biology, cell biology, and developmental biology. This book discusses amphibian development with an emphasis on integrating morphological approach with molecular and cell biology. Included are chapters on hormonal regulation, morphological changes, biochemical and cellular changes, mechanisms of thyroid action, gene regulation by thyroid hormone and functional aspects.

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Editorial Reviews

From the Publisher
"The bulk of this book is on more recent molecular analyses...A summary and comparison is provided for the gene regulation programs induced by thyroid hormone..." (SciTech Book News, March 2001)

"This is the first work of its kind...and will serve well as a textbook for...students, or as a reference for scientists..." (The Quarterly Review of Biology, Vol. 76, No. 4, December 2001)

SciTech Book News
The bulk of this book is on more recent molecular analyses...A summary and comparison is provided for the gene regulation programs induced by thyroid hormone...
SciTech Book News
The bulk of this book is on more recent molecular analyses...A summary and comparison is provided for the gene regulation programs induced by thyroid hormone...
Booknews
Integrating findings from recent studies with earlier observations, Shi (head of the Molecular Morphogenesis Unit, NICHD/NIH) presents overview chapters on various factors that influence metamorphosis in different classes of amphibians. The bulk of the book is on more recent molecular analyses including the thyroid hormone signal transduction pathway, especially transcriptional regulation mechanisms by thyroid hormone receptors. A summary and comparison is provided for the gene regulation programs induced by thyroid hormone in several organs; then several chapters focus on functional and mechanistic implications of the molecular findings on the thyroid hormone response genes in tissue transformations. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780471244752
  • Publisher: Wiley
  • Publication date: 10/28/1999
  • Edition number: 1
  • Pages: 292
  • Product dimensions: 6.36 (w) x 9.65 (h) x 0.81 (d)

Table of Contents

An Overview of Amphibian Metamorphosis.

Hormonal Regulation.

Morphological Changes During Anuran Metamorphosis.

Cellular and Biochemical Changes.

Mechanism of Thyroid Hormone Action.

Gene Regulation by Thyroid Hormone.

Functional Implication of Thyroid Hormone Response Genes: Transcription Factors in the Thyroid Hormone Signal Transduction Cascade.

Competence and Tissue-specific Temporal Regulation of Amphibian Metamorphosis.

Thyroid Hormone Regulation and Functional Implication of Cell-Cell and Cell-Extracellular Matrix Interactions during Tissue Remodeling.

Model Systems and Approaches to Study the Molecular Mechanisms of Amphibian Metamorphosis.

Comparison with Insect Metamorphosis.

Roles of Thyroid Hormone and Its Receptors in Mammalian Development and Human Diseases.

References.

Index.

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