Analysis of Drug Impurities / Edition 1

Hardcover (Print)
Buy New
Buy New from
Used and New from Other Sellers
Used and New from Other Sellers
from $182.85
Usually ships in 1-2 business days
(Save 24%)
Other sellers (Hardcover)
  • All (8) from $182.85   
  • New (6) from $182.85   
  • Used (2) from $233.27   


The presence of impurities, even in small amounts, may affect the efficacy and safety of pharmaceuticals. The methods for detecting and controlling them are subject to continuous review and improvement. Characterisation of impurities is a crucial aspect of drug development and approval, and is central to quality control.This book provides a source of reference on the techniques available for accurate identification and quantification of drug impurities, and it brings together all the relevant disciplines within one volume for the first time.

Read More Show Less

Editorial Reviews

From the Publisher
"This is a unique book; the editors are to be conrgatulated on persuading their industrial colleagues to write chapters, providing an industrial focus on analytical issues. This is a useful volume which fills a gap in the literature... I would recommend the book to all process and analytical chemists."
Trevor Laird"This book can be recommended to not only analytical chemists but also scientists working in the field of pharmaceutical analysis."
Annals of Bioanalytical Chemistry
Read More Show Less

Product Details

  • ISBN-13: 9781405133586
  • Publisher: Wiley
  • Publication date: 4/28/2007
  • Series: Sheffield Analytical Chemistry Series, #10
  • Edition number: 1
  • Pages: 288
  • Product dimensions: 6.10 (w) x 9.30 (h) x 0.80 (d)

Meet the Author

Richard Smith is Director, Analytical Sciences at GlaxoSmithKline Research and Development, Tonbridge, UK and Michael Webb is Director, Analytical Sciences at GlaxoSmithKline Research and Development, Stevenage, UK.

Contributors to the book:
Dr Linda Ng
Dr George Lunn
Dr Patrick Faustino
Dr Dave Elder
Dr Mark R. Hadley
Dr Peter Skett
Dr Gary E. Martin
Dr Ian Jones
Dr Janet Hammond
Dr Gerald Terfloth
Dr Frank Cottee

Read More Show Less

Table of Contents

1. Organic impurities in drug substances: origin, control and measurement.


2. Organic impurities in drug products: origin, control and measurement.

3. Stereochemical impurities.


4. Low level measurement of potent toxins.


5. A systematic approach to impurity identification.


6. The use chromatography and on-line structural elucidation using spectroscopy .

7. Preparative isolation of impurities.


8. Impact of continuous processing.



Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)