Analytical Profiles of Drug Substances and Excipients

Hardcover (Print)
Buy New
Buy New from
Used and New from Other Sellers
Used and New from Other Sellers
from $18.71
Usually ships in 1-2 business days
(Save 93%)
Other sellers (Hardcover)
  • All (9) from $18.71   
  • New (5) from $26.66   
  • Used (4) from $18.71   


Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Analytical Profiles of Drug Substances and Excipients, brings the latest information together in one source.

Audience: Analytical, pharmaceutical, and medical chemists; pharmacologists.

Read More Show Less

Editorial Reviews

A compilation of drug substances summarizing physical and chemical data, analytical methods, routes of compound preparation, and degradation pathways. Volume 24 of the distinguished reference series profiles carbenoxolone sodium, clarithromycin, crospovidone, fluvoxamine maleate, gadoteridol, guar gum, mafenide acetate, maltodextrin, nalmefene hydrochloride, polyvinyl alcohol, sertraline hydrochloride, solasodine, starch, and tobramycin. Annotation c. Book News, Inc., Portland, OR (
From the Publisher
"Volume 25 of this series continues the long tradition of well-written and well-documented profiles of drug substances and pharmaceutical excipients that should be essential readings for the practicing pharmaceutical scientist...What makes this and the entire series of volumes a valuable work is the thoroughness of the presented data and the detail which is paid to consistency. It is hopeful that pharmaceutical scientists worldwide will help to maintain the outstanding reputation of this series by contributing profiles. The price of each volume is reasonable and can be purchased for a personal library. The entire 25 volume set should definitely be available in academic, industrial, and governmental laboratories where pharmaceutical research is being conducted."
—James T. Stewart, College of Pharmacy, The University of Georgia, JOURNAL OF PHARMACEUTICAL and BIOMEDICAL ANALYSIS
Praise for the Series
"This volume and the entire 24 volumes are highly recommended for single individual use or by groups of scientists when placed in a corporate, government, or academic library. There is no comparable series of books that provides this important data in such a timely and meaningful manner."
"This series was first published in 1972 and represents a very important contribution to the practice of pharmaceutical analysis...This volume represents an excellent overview of physical, chemical, and biochemical properties of some regularly prescribed drugs."
—Brian J. Clark in THE ANALYST
Read More Show Less

Product Details

Meet the Author

Prior to forming the Center for Pharmaceutical Physics, Dr. Brittain was Vice President for Pharmaceutical Development of Discovery Laboratories, Inc. Before that, he served as Director of Pharmaceutical Development at Ohmeda, Inc., and also led a variety of groups within the Analytical R&D department at Bristol-Myers Squibb. Dr. Brittain is a graduate of Queens College (B.S., 1970; M.S. 1972), and of the City University of New York (Ph.D. in physical chemistry, 1975). He was a postdoctoral fellow at the University of Virginia, and has held faculty positions at Ferrum College (Assistant Professor of Chemistry) and Seton Hall University (Associate Professor of Physical and Inorganic Chemistry). He has been Adjunct Professor of Pharmaceutics at Rutgers University, and presently holds a position as Visiting Research Scientist in the Chemistry Department at Lehigh University.

Dr. Brittain has authored approximately 225 research publications and book chapters, and has edited the monographs Physical Characterization of Pharmaceutical Solids, Polymorphism in Pharmaceutical Solids, and Analytical Applications of Circular Dichroism. Dr. Brittain is a member of the editorial boards of Pharmaceutical Research, Journal of Pharmaceutical Sciences, Pharmaceutical Development and Technology PharmSci, Pharmaceutical Technology, Journal of Pharmaceutical and Biomedical Analysis, Saudi Pharmaceutical Journal, Chirality, and Instrumentation Science and Technology. He is also the Editor for the book series Analytical Profiles of Drug Substances and Excipients, and is Chairman of the USP Committee 'Excipients: Substances and Characterization as a member of the Council of Experts. Dr. Brittain was elected as a Fellow of the American Association of Pharmaceutical Sciences (AAPS) in 1991, and received the AAPS Research Achievement Award in Analysis and Pharmaceutical Quality in 1998.

Read More Show Less

Table of Contents

Affiliations of Editors and Contributors
Amoxicillin 1
Diltiazem Hydrochloride 53
Diosgenin 99
Econazole Nitrate 125
Hyoscyamine 153
Indapamide 229
Lincomycin Hydrochloride 269
Lomefloxacin 321
Methocarbamol 371
Natamycin 399
Salicylic Acid 421
Sulfacetamide 471
Talc 511
Tolnaftate 543
Triamterene 571
Cumulative Index 607
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)