Anatomy of a Scientific Discovery

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first Good [ No Hassle 30 Day Returns ] Publisher: Bantam Pub Date: 5/1/1989 Binding: Paperback Pages: 244.

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1989 Trade paperback Good. No dust jacket as issued. A moderate amount of wear on Cover and interior pages. (W4) Trade paperback (US). Glued binding. 244 p. Audience: ... General/trade. Read more Show Less

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Overview

A true scientific page-turner that traces a remarkable scientific breakthrough (the isolation of endorphins in the brain) as dedicated scientists race--not only with their fellow scientists--but against time and the profit hungry giant pharmaceutical companies.

This chronicles the fascinating discovery of endorphins, the body's natural painkiller.

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More About This Book

Overview

A true scientific page-turner that traces a remarkable scientific breakthrough (the isolation of endorphins in the brain) as dedicated scientists race--not only with their fellow scientists--but against time and the profit hungry giant pharmaceutical companies.

This chronicles the fascinating discovery of endorphins, the body's natural painkiller.

Editorial Reviews

Publishers Weekly
An international race during the 1970s among scientists in the U.S. and Scotland to isolate endorphinsnatural, morphine-like substances present in the brainis recounted in clear and colorful detail by science writer Goldberg (coauthor of Flowers in the Blood). He gives an account of the discovery (by the team of Hans Kosterlitz and John Hughes, in a poorly funded lab in Aberdeen) of a nonaddictive narcotic chemical in pigs' brains, and then follows with a contrasting account of the high-tech research conducted by scientists at American universities on opiate receptors and experiments designed to stimulate natural pain-blocking, much of the American effort motivated by the need to combat heroin addiction. In 1976, the controversy-fraught laboratory competition was superceded by the race among drug companies to develop the most successful of the 20 types of opiate peptides; the prize would be domination of a market serving an estimated 20 million chronic pain sufferers in the U.S. alone. While some researchers have sought inconclusively to establish a relationship between endorphins and mental illness, others have focused on a proposed linkage between endorphins and pleasure, learning, stress and sexual response. (May)

Product Details

  • ISBN-13: 9780553346312
  • Publisher: Random House Publishing Group
  • Publication date: 5/1/1989
  • Pages: 244
  • Product dimensions: 5.50 (w) x 8.50 (h) x 0.50 (d)

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Sort by: Showing 1 Customer Review

  • Posted February 23, 2010

    more from this reviewer

    I Also Recommend:

    9780380782093 9780141186184 9780963412652

    Educational

    I found this at a library book sale, along with about 10 other books for $3. What interested me was the form in which this story takes, the subject of the narrative, and that it would satisfy and feed my curiosity in the science of the brain and nervous system. I enjoyed learning about the life of lab researchers and the social networking of the scientific and medical communities. I found that when Goldberg broadened the focus from Kosterlitz and Hughes in Aberdeen to the development of the research within other institutions, that I missed the original characters and wanted to read about what they were doing as things developed. There is much scientific jargon that I see as essential to the narrative and understanding, but I am not well-versed in those details. Because of that, I probably missed out on fully appreciating it, while people more familiar with chemistry and biology would gain the most comprehension of it. Still, I do not regret reading it and learning about the discipline in a less simplistic manner. As a reader who appreciates dabbling in many things, and things being explained appropriately (clear enough for a general audience, but not simplified excessively), the book was enlightening and worth reading. I think I prefer the English way of endorsing and funding scientific research to the American way, which gives more room to truly explore rather than rushing the researchers to produce results as quickly as is possible. This book highlights the nature of scientific competition, and the need for action, lest (if the research of actual great importance) someone else vying for recognition, etc. make the discovery and publish their findings first. In that sense, there is some appropriate amount of suspense, where I was finding myself rooting for the original team of Kosterlitz and Hughes, hoping their competitors didn't "steal" their discovery and holding claim to it, when it seemed rightfully that in this case, belonging to the Aberdeen institution. One of the researchers in this race for endorphins' usefulness, Dr. Candace Pert, apparently endorses and approves of this book, as is attested on the back cover with her review of it. If you enjoy learning, and discovering the life of medical research and how scientists really make breakthrough discoveries, then pick up this narrative.

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