Anatomy of a Scientific Discovery

( 1 )

Overview

A true scientific page-turner that traces a remarkable scientific breakthrough (the isolation of endorphins in the brain) as dedicated scientists race--not only with their fellow scientists--but against time and the profit hungry giant pharmaceutical companies.

This chronicles the fascinating discovery of endorphins, the body's natural painkiller.

Read More Show Less
... See more details below
Other sellers (Paperback)
  • All (35) from $1.99   
  • New (5) from $8.94   
  • Used (30) from $1.99   
Sending request ...

Overview

A true scientific page-turner that traces a remarkable scientific breakthrough (the isolation of endorphins in the brain) as dedicated scientists race--not only with their fellow scientists--but against time and the profit hungry giant pharmaceutical companies.

This chronicles the fascinating discovery of endorphins, the body's natural painkiller.

Read More Show Less

Editorial Reviews

Publishers Weekly - Publisher's Weekly
An international race during the 1970s among scientists in the U.S. and Scotland to isolate endorphinsnatural, morphine-like substances present in the brainis recounted in clear and colorful detail by science writer Goldberg (coauthor of Flowers in the Blood). He gives an account of the discovery (by the team of Hans Kosterlitz and John Hughes, in a poorly funded lab in Aberdeen) of a nonaddictive narcotic chemical in pigs' brains, and then follows with a contrasting account of the high-tech research conducted by scientists at American universities on opiate receptors and experiments designed to stimulate natural pain-blocking, much of the American effort motivated by the need to combat heroin addiction. In 1976, the controversy-fraught laboratory competition was superceded by the race among drug companies to develop the most successful of the 20 types of opiate peptides; the prize would be domination of a market serving an estimated 20 million chronic pain sufferers in the U.S. alone. While some researchers have sought inconclusively to establish a relationship between endorphins and mental illness, others have focused on a proposed linkage between endorphins and pleasure, learning, stress and sexual response. (May)
Read More Show Less

Product Details

  • ISBN-13: 9780553346312
  • Publisher: Random House Publishing Group
  • Publication date: 5/1/1989
  • Pages: 244
  • Product dimensions: 5.50 (w) x 8.50 (h) x 0.50 (d)

Customer Reviews

Average Rating 3
( 1 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(1)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously
Sort by: Showing 1 Customer Reviews
  • Posted February 23, 2010

    more from this reviewer

    I Also Recommend:

    Educational

    I found this at a library book sale, along with about 10 other books for $3. What interested me was the form in which this story takes, the subject of the narrative, and that it would satisfy and feed my curiosity in the science of the brain and nervous system. I enjoyed learning about the life of lab researchers and the social networking of the scientific and medical communities. I found that when Goldberg broadened the focus from Kosterlitz and Hughes in Aberdeen to the development of the research within other institutions, that I missed the original characters and wanted to read about what they were doing as things developed. There is much scientific jargon that I see as essential to the narrative and understanding, but I am not well-versed in those details. Because of that, I probably missed out on fully appreciating it, while people more familiar with chemistry and biology would gain the most comprehension of it. Still, I do not regret reading it and learning about the discipline in a less simplistic manner. As a reader who appreciates dabbling in many things, and things being explained appropriately (clear enough for a general audience, but not simplified excessively), the book was enlightening and worth reading. I think I prefer the English way of endorsing and funding scientific research to the American way, which gives more room to truly explore rather than rushing the researchers to produce results as quickly as is possible. This book highlights the nature of scientific competition, and the need for action, lest (if the research of actual great importance) someone else vying for recognition, etc. make the discovery and publish their findings first. In that sense, there is some appropriate amount of suspense, where I was finding myself rooting for the original team of Kosterlitz and Hughes, hoping their competitors didn't "steal" their discovery and holding claim to it, when it seemed rightfully that in this case, belonging to the Aberdeen institution. One of the researchers in this race for endorphins' usefulness, Dr. Candace Pert, apparently endorses and approves of this book, as is attested on the back cover with her review of it. If you enjoy learning, and discovering the life of medical research and how scientists really make breakthrough discoveries, then pick up this narrative.

    Was this review helpful? Yes  No   Report this review
Sort by: Showing 1 Customer Reviews

If you find inappropriate content, please report it to Barnes & Noble
Why is this product inappropriate?
Comments (optional)