Androgen Excess Disorders in Women / Edition 1

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This thoroughly revised and comprehensive edition of a highly praised classic, Androgen Excess Disorders in Women covers the growing importance of polycystic ovary syndrome (PCOS) as the most prevalent androgen excess disorder in women. This volume addresses the latest research findings on the etiology, pathophysiology, clinical manifestations, genetics, and consequences of androgen excess disorders in women, including PCOS, nonclassic adrenal hyperplasia, androgen-secreting tumors, severe insulin-resistant hyperandrogenic syndromes, and rarer causes of androgen excess and hirsutism.

Full consideration is given to the long-term consequences of androgen excess and PCOS, including endometrial hyperplasia and carcinoma, infertility, cardiovascular and lipoprotein abnormalities, osteoporosis, obesity and glucose intolerance, and psychosocial problems. In addition, detailed information on the methods now available for diagnosis and treatment of these disorders are extensively reviewed.

Cutting-edge and timely, the second edition of Androgen Excess Disorders in Women: Polycystic Ovary Syndrome and Other Disorders serves as an indispensable guide and resource for clinicians and researchers alike in the care and study of women with androgen excess disorders.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Suma Dronavalli, MD (University of Chicago Medical Center)
Description: This is a thoughtful, focused approach to androgen excess in women. The book is well organized and the format makes identification of specific topics easy.
Purpose: According to the preface, the purpose is to provide a guide and resource for all clinicians and researchers in the field of androgen excess. It is nice to find so many topics that are usually addressed in a fragmented fashion in one source discussed by leaders in the field. The editors achieved their objective.
Audience: This book is targeted at both researchers and clinicians in the field of androgen excess and it serves that audience well. The editors and many of the authors are well known in the field.
Features: "The chapters are divided according to physiology, uncommon causes of androgen excess, polycystic ovary syndrome, and evaluation and treatment. Each of the individual chapters is also well organized with a summary, clear topic headings, conclusions, future directions, and key points. The book is all in black and white and the use of figures varies between chapters. Most chapters had helpful figures, but a few chapters were lacking illustrations. "
Assessment: This is a good resource. It is helpful to have so many aspects of androgen excess addressed in a single source by knowledgeable authors.
From the Publisher
From the reviews:

"...a timely update of a rapidly mushrooming area of the reproductive literature." -TRENDS in Endocrinology andf Metabolism

"This is a thoughtful, focused approach to androgen excess in women. The book is well organized and the format makes identification of specific topics easy. … This book is targeted at both researchers and clinicians in the field of androgen excess and it serves that audience well. … a good resource. It is helpful to have so many aspects of androgen excess addressed in a single source by knowledgeable authors." (Suma Dronavalli, Doody’s Review Service, December, 2006)

New England Journal of Medicine
It will be an often-consulted reference book for endocrinologists, internists, pediatricians, and gynecologists who care for women with hirsutism, and I recommend it for students, of all ages, with an interest in this complex field.
David P. Cohen
This book on androgen excess disorders in women fills a void in the gynecologic literature. Its three editors have assembled the work of 99 authors from 11 countries. Its aim is ""to provide a thorough yet concise overview of the current state of the art of androgen excess research, diagnosis, and therapy."" Although hardly concise at 830 pages, it otherwise fulfills its aims, providing an excellent overview of an often incompletely understood group of disorders. The intended audience is broad, encompassing investigators and clinicians dealing with androgenized patients, including medical, reproductive, and pediatric endocrinologists, gynecologists, dermatologists, and generalists. While the book may provide too much information for some generalists, there are certainly chapters relevant to the general clinician. The book is an outstanding reference for clinical endocrinologists, as well as basic and clinical research scientists. The book benefits from contributions from a wide variety of well respected experts, the references are current, and the book is very well organized. There is a consistent style, despite a large number of contributors, and the synopsis at the end of each chapter is an excellent idea. The diagrams explaining molecular mechanisms are also excellent. This work is an outstanding reference for the specialist dealing with androgen disorders in women. It should be a part of every endocrinology and obstetric and gynecology library, as well as the personal library of the physician treating androgenized females.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781588296634
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 9/28/2006
  • Series: Contemporary Endocrinology Series
  • Edition description: 2007
  • Edition number: 1
  • Pages: 488
  • Product dimensions: 10.00 (w) x 7.00 (h) x 1.06 (d)

Table of Contents

I. Introduction

A Brief History of Androgen Excess
Ricardo Azziz

II. Physiology of Androgens

Ovarian and Adrenal Androgen Biosynthesis and Metabolis
Walter L. Miller, David H. Geller, and Mitchell Rosen

Androgens Throughout the Life of Women
C. Richard Parker, Jr.

Physiologic Effects of Androgens in Women
T. Keta Hodgson and Glenn D. Braunstein

Androgen Measurements: Methods, Interpretation and Limitations
Frank Z. Stanczyk

III. Pathophysiology of Androgen Excess

Androgen-Secreting Adrenal and Ovarian Neoplasms
Michel Pugeat, Gérald Raverot, Ingrid Plotton, Aude Brac de la Perrière, Pascale Mirakian, Henri Déchaud, Nicole Berger, and Jean Louis Peix

Cushing's Syndrome Acromegaly and Androgen Excess
Anne-Céline REYSS, Didier Dewailly

The Non Classic Adrenal Hyperplasias
Didier Dewailly and Ricardo Azzizb

Pregnancy-Related Androgen Excess
Howard D. McClamrock

Drug-Induced Hyperandrogenism
Christine Cortet-Rudelli and Didier Dewailly

The Severe Insulin Resistant Hyperandrogenic Syndromes
David E. Moller, Antonio Vidal-Puig, and Ricardo Azziz

Idiopathic Hirsutism
Enrico Carmina

Definition and Epidemiology of the Polycystic Ovary Syndrome
Ricardo Azziz

Clinical Features of PCOS
W. Futterweit, E. Diamanti-Kandarakis, and Ricardo Azziz

Biochemical Features of the Polycystic Ovary Syndrome
Adam Balen

Ovarian Histology, Morphology and Ultrasonography in PCOS
Sophie Jonard, Yann Robert, Yves Ardaens, and Didier Dewailly

Hypothalamic-Pituitary-Gonadotropic Dysfunction in PCOS
R. Jeffrey Chang and Rinku V. Mehta

Ovarian Steroidogenic Abnormalities in PCOS
Denis A. Magoffin

Hypothalamic-Pituitary Adrenal Dysfunction in Polycystic Ovary Syndrome
Bulent O.Yildiz, Enrico Carmina, and Ricardo Azziz

The Genetic Basis of Polycystic Ovary Syndrome
Mark O. Goodarzi

Pediatric Hyperandrogenism
Kathleen M. Hoeger

Environmental Factors in the Polycystic Ovary Syndrome
Marie-France Hivert and Jean-Patrice Baillargeon

Animal Models and Fetal Programming of PCOS
David H. Abbott, Daniel A. Dumesic, Jon E. Levine, Andrea Dunaif, and Vasantha Padmanabhan

Insulin Resistance and Hyperinsulinism in PCOS
Paulina A. Essah and John E. Nestler

The Endocrine Impact of Obesity and Body Habitus in PCOS
Pasquali Renato and Gambineri Alessandra

Molecular Mechanisms of Insulin Resistance in PCOS
Theodore P. Ciaraldi

Menstrual Dysfunction and Endometrial Neoplasia
Abdulkadir Wagley and Paul Hardiman

Beta Cell Dysfunction, Glucose Intolerance, and Diabetes in PCOS
David A. Ehrmann

Hypertension, and Cardiovascular and Lipoprotein Abnormalities
Francesco Orio and Stefano Palomba

Reproductive and Obstetrical Consequences of Polycystic Ovary Syndrome
Mary C. Johnson and Richard S. Legro

Psychosocial and Quality-of-Life Consequences of Androgen Excess
Onno E. Janssen, Susanne Hahn, and Sigrid Elsenbruch

Overview of Long-Term Morbidity and Economic Cost of PCOS
Ricardo Azziz

IV. Evaluation and Treatment of Androgen Excess

Clinical and Hormonal Evaluation of Androgen Excess
Ricardo Azziz

Ovarian Suppression and Treatment of Hirsutism
Paolo Moghetti

Polycystic Ovary Syndrome and Ovulation Induction
Bulent O. Yildiz and Ricardo Azziz

In Vitro Fertilization for Polycystic Ovary Syndrome
Hanadi Ba-Akdah, Ezgi Demirtas, Hananel Holzer, William Buckett, and Seang Lin Tan

The Surgical Management of Polycystic Ovary Syndrome
Adam Balen

Use of Insulin Sensit

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