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Doody's Review ServiceReviewer: Rishi G Anand, MD (Ochsner Clinic Foundation)
Description: The authors of this book bring to the forefront of cardiovascular medicine the "no-option patients, " people who live with end-stage ischemic heart disease and are either no longer candidates for percutaneous or surgical revascularization or have exhausted or failed these modalities.
Purpose: The authors summarize pertinent basic science, clinical, and experimental research in order to provide a roadmap to physicians caring for patients with end-stage ischemic heart disease.
Audience: The book provides internists, cardiovascular specialists, researchers, and industry the most current treatment strategies espoused by internationally recognized pioneers and opinion leaders for helping patients with end-stage ischemic heart disease and peripheral vascular disease.
Features: The authors set the framework of managing "no-option" patients by discussing the mechanics of coronary microcirculation, then novel cellular and genetic therapeutic targets. Highlights of the book include new drug delivery systems, stem-cell therapy, gene therapy, and a discussion of transmyocardial laser revascularization.
Assessment: This book masterfully and authoritatively blends expert opinion with quality scientific research to provide specialists with insight into current treatment options for end-stage ischemic patients and future possibilities.