Animal Models in Toxicology, Second Edition / Edition 2

Hardcover (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $150.75
Usually ships in 1-2 business days
Other sellers (Hardcover)
  • All (4) from $150.75   
  • New (1) from $164.90   
  • Used (3) from $150.75   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$164.90
Seller since 2009

Feedback rating:

(9966)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
New Book. Shipped from US within 4 to 14 business days. Established seller since 2000

Ships from: Secaucus, NJ

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
Page 1 of 1
Showing All
Close
Sort by

Overview

Reflecting more than a decade’s worth of changes, Animal Models in Toxicology, Second Edition is a practical guide to the common statistical problems encountered in toxicology and the methodologies that are available to solve them. The book presents a historical review of the use of animal models and an overview of broad considerations of metabolism and relevance used in toxicology. Individual chapters covering the eight major species used in toxicology and experimental biology form the core of the book. With contributions from experts in toxicology, toxicological pathology, and species-specific metabolism, each of these chapters provide an excellent introductory “course” along with guidance to the literature for more detailed understanding.

The book goes on to make the case for a range of species not commonly used for safety assessment studies but which may provide useful alternative models for some specific endpoints. The chapter authors discuss special considerations regarding the evaluation and interpretation of the clinical pathology of the eight major model species as well as how to select a model species and how to extrapolate the results to humans. They detail potential pitfalls and situations that cause either human or model to be significantly more sensitive than the other or totally irrelevant to each other. The book concludes with an overview of the increasingly complex laws and regulations that govern how laboratory animals are obtained, maintained, and utilized, and an appendix that provides a quick guide to commercial sources of laboratory animals.

Read More Show Less

Editorial Reviews

American Journal of Pharmaceutical Education
...a valuable reference for toxicologists, pharmacologists, biochemists, physiologists, and other biomedical scientists who need authoritative information on the use of animal models in drug and chemical evaluation and risk assessment for teaching, research, testing, or regulatory purposes. This book should be in the personal libraries of the professionals mentioned above as well as in the libraries of all educational, industrial, commercial, regulatory, and research institutions serving those disciplines...an excellent choice as a supplemental reference text for a course in toxicological methods or research techniques.
Indian Journal of Toxicology
...highly recommended.
International Journal of Biochemistry
...deals with the toxicology, pathology, and metabolism in all the standard animals with a chapter each of the following: rat, mouse, hamster, guinea pig, rabbit, ferret, dog, non human primates. There are also chapters on alternative species (earthworms, fish, minipigs); model selection and scaling; susceptibility factors; legal regulations; commercial sources of animals. All those who use laboratory animals will find this a useful book to read. Those carrying out drug tests will find it essential reading.
Journal of Pharmaceutical Pharmacology
...the book achieves its aim admirably. Clear descriptions with excellent illustrations are given for procedures such as dosing and removal of body fluids for both rat and mouse, followed by an outline of the pathology that may affect the design and interpretation of experiments.
American Journal of Pharmaceutical Ed.
...a valuable reference for toxicologists, pharmacologists, biochemists, physiologists, and other biomedical scientists who need authoritative information on the use of animal models in drug and chemical evaluation and risk assessment for teaching, research, testing, or regulatory purposes. This book should be in the personal libraries of the professionals mentioned above as well as in the libraries of all educational, industrial, commercial, regulatory, and research institutions serving those disciplines...an excellent choice as a supplemental reference text for a course in toxicological methods or research techniques.
International Journal of Biochemistry
...deals with the toxicology, pathology, and metabolism in all the standard animals with a chapter each of the following: rat, mouse, hamster, guinea pig, rabbit, ferret, dog, non human primates. There are also chapters on alternative species (earthworms, fish, minipigs); model selection and scaling; susceptibility factors; legal regulations; commercial sources of animals. All those who use laboratory animals will find this a useful book to read. Those carrying out drug tests will find it essential reading.
JPP
...the book achieves its aim admirably. Clear descriptions with excellent illustrations are given for procedures such as dosing and removal of body fluids for both rat and mouse, followed by an outline of the pathology that may affect the design and interpretation of experiments.
Journal of Pharmaceutical Pharmacology
Indian Journal of Toxocology
...highly recommended.
Read More Show Less

Product Details

  • ISBN-13: 9780824754075
  • Publisher: Taylor & Francis
  • Publication date: 10/28/2006
  • Series: Drug and Chemical Toxicology Series
  • Edition description: REV
  • Edition number: 2
  • Pages: 952
  • Product dimensions: 7.20 (w) x 10.10 (h) x 2.40 (d)

Table of Contents

Introduction, S.C. Gad The Mouse
Toxicology, S.C. Gad
Pathology, C.H. Frith, D.G. Goodman, and B.G. Boysen
Metabolism, S.C. Gad The Rat
Toxicology, M.D. Johnson
Pathology, S.C. Gad
Metabolism, S.C. Gad The Hamster
Toxicology, S.C. Gad
Pathology, F.G. Hess
Metabolism, S.C. Gad
The Guinea Pig
Toxicology, S.C. Gad
Pathology, J.C. Peckham
Metabolism, S.C. Gad The Rabbit
Toxicology, C.M. Salamon and K.M. MacKenzie
Pathology, J.C. Peckham
Metabolism, S.C. Gad The Ferret
Toxicology, D.E. McLain
Pathology, S. Chandra
Metabolism, S.C. Gad The Dog
Toxicology, G.C. Haggerty
Pathology, J.C. Peckham and R.W. Thomassen
Metabolism, S.C. Gad Primates
Toxicology, M.D. Walker, J.K. Nelson, and J.C. Bernal
Pathology, G.B. Baskin
Metabolism, S.C. Gad The Minipig
Toxicology, S.C. Gad
Pathology, Z. Dincer and O. Svendsen
Metabolism, M.T. Skaanild
Alternative, S.C. Gad
Clinical Pathology of Laboratory Animals, R.L. Hall
Model Selection and Scaling, S.C. Gad
Susceptibility Factors, S.C. Gad
Laws and Regulations Governing Animal Care and Use in Research, S.C. Gad
Appendix: Commercial Sources of Laboratory Animals, S.C. Gad Index

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)