Animal Models of Human Cognitive Aging / Edition 1

Animal Models of Human Cognitive Aging / Edition 1

by Jennifer L. Bizon
     
 

ISBN-10: 1588299961

ISBN-13: 9781588299963

Pub. Date: 12/12/2008

Publisher: Springer-Verlag New York, LLC

Significant improvements in lifestyle and medical science are leading to an ever increasing elderly population in the United States and other developed nations. The U.S. census bureau estimates the number of people over 65 will nearly double by 2030, and that the elderly population will comprise nearly one-fifth of the world's entire population within the next

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Overview

Significant improvements in lifestyle and medical science are leading to an ever increasing elderly population in the United States and other developed nations. The U.S. census bureau estimates the number of people over 65 will nearly double by 2030, and that the elderly population will comprise nearly one-fifth of the world's entire population within the next twenty years. In Animal Models of Human Cognitive Aging, Jennifer Bizon, Alisa Woods, and a panel of international authorities comprehensively discuss the use of animal models as a tool for understanding cognitive changes associated with the aging process. The book provides substantive background on the newest and most widely used animal models in studies of cognition and aging, while detailing the normal and pathological processes of brain aging of humans in relation to those models. Additional chapters comprehensively review frontal cortical deficits and executive function in primates as related to humans, and the use of transgenic modulation in mice to model Alzheimer's and other age-related diseases. Groundbreaking and authoritative, Animal Models of Human Cognitive Aging provides a valuable resource for Neuroscientists, Gerontological Scientists, and all aging medicine researchers, while serving as a primer for understanding current brain aging studies.

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Product Details

ISBN-13:
9781588299963
Publisher:
Springer-Verlag New York, LLC
Publication date:
12/12/2008
Series:
Aging Medicine Series
Edition description:
2009
Pages:
208
Product dimensions:
6.30(w) x 9.40(h) x 0.60(d)

Table of Contents

Chapter 1. Normal and Pathological Aging – From Animals to Humans Nicole C. Berchtold and Carl W. Cotman Chapter 2. Non-Human Primate Models of Cognitive Aging Agnès Lacreuse and James G. Herndon Chapter 3. Age-related Effects on Prefrontal Cortical Systems: Translating Between Rodents, Nonhuman Primates, and Humans Mark G. Baxter Chapter 4. Comparison of Different Cognitive Rat Models of Human Aging Candi LaSarge and Michelle Nicolle Chapter 5. Mouse Models of Cognitive Aging: Behavioral Tasks and Neural Substrates Michael E. Calhoun Chapter 6. Impact of Aß and Tau on Cognition in Mouse Models of Alzheimer’s Disease Maya A. Koike, Kristoffer Myczek, Kim N. Green and Frank M. LaFerla Chapter 7. Hormonal Influences on Brain Aging and Age-Related Cognitive Decline Danielle K Lewis and Farida Sohrabji Chapter 8. Timing Deficits in Aging and Neuropathology Fuat Balci, Warren H. Meck, Holly Moor, and Dani Brunner

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