Antibiotic Resistance: Understanding and Responding to an Emerging Crisis

Antibiotic Resistance: Understanding and Responding to an Emerging Crisis

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by Karl S. Drlica, David S. Perlin
     
 

Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is

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Overview

Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.

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Product Details

ISBN-13:
9780131387737
Publisher:
FT Press
Publication date:
02/23/2011
Pages:
288
Sales rank:
1,488,187
Product dimensions:
6.90(w) x 10.00(h) x 0.90(d)

Related Subjects

Table of Contents

Preface xv

Chapter 1 Introduction to the Resistance Problem 1

Chapter 2 Working with Pathogens 17

Chapter 3 A Survey of Antibiotics 31

Chapter 4 Dosing to Cure 55

Chapter 5 Emergence of Resistance 73

Chapter 6 Movement of Resistance Genes Among Pathogens 91

Chapter 7 Transmission of Resistant Disease 105

Chapter 8 Surveillance 125

Chapter 9 Making New Antibiotics 139

Chapter 10 Restricting Antibiotic Use and Optimizing Dosing 149

Chapter 11 Influenza and Antibiotic Resistance 167

Chapter 12 Avoiding Resistant Pathogens 177

Afterword A Course of Action 203

Appendix A Molecules of Life 207

Appendix B Microbial Life Forms 221

Glossary 227

Literature Cited 233

Index 251

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