Antibiotics: Actions, Origins, Resistance / Edition 1

Hardcover (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $71.15
Usually ships in 1-2 business days
(Save 28%)
Other sellers (Hardcover)
  • All (7) from $71.15   
  • New (3) from $172.77   
  • Used (4) from $71.15   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$172.77
Seller since 2008

Feedback rating:

(193)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
1555812546 New. Looks like an interesting title!

Ships from: Naperville, IL

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
$215.00
Seller since 2014

Feedback rating:

(165)

Condition: New
Brand new.

Ships from: acton, MA

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
$215.00
Seller since 2014

Feedback rating:

(165)

Condition: New
Brand new.

Ships from: acton, MA

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
Page 1 of 1
Showing All
Close
Sort by

Overview

A comprehensive account of the structural classes of antibiotics that have impacted human infectious disease.
• Provides an introduction to antibiotics and examines how antibiotics block specific proteins acting in essential bacterial processes and how the molecular structure of the small-molecule drugs enables their antibiotic activity.
• Explores the development of bacterial resistance to antibiotics, including the molecular logic that microbial producers of antibiotics use for self-protection.
• Addresses the molecular logic of antibiotic biosynthesis, starting with regulatory networks that control gene transcription of secondary metabolites in streptomycetes, and examines the prospects for broadening the base of bacterial targets and also where new antibiotics are likely to emerge, including both synthetic chemical efforts and natural products.
Read More Show Less

Product Details

  • ISBN-13: 9781555812546
  • Publisher: ASM Press
  • Publication date: 2/28/2003
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 345
  • Product dimensions: 7.10 (w) x 10.10 (h) x 0.90 (d)

Table of Contents

Preface
Sect. I Introduction to Antibiotics 1
Ch. 1 Antibiotics: Initial Concepts 3
Sect. II Validated Targets and Major Antibiotic Classes 11
Ch. 2 Introduction to Major Antibiotic Classes and Modes of Action 13
Ch. 3 Antibiotics That Act on Cell Wall Biosynthesis 23
Ch. 4 Antibiotics That Block Bacterial Protein Biosynthesis 51
Ch. 5 Antibiotics That Block DNA Replication and Repair: the Quinolones 71
Ch. 6 Other Targets of Antibacterial Drugs 79
Sect. III Antibiotic Resistance 89
Ch. 7 Natural and Producer Immunity versus Acquired Resistance 91
Ch. 8 Enzymatic Destruction or Modification of the Antibiotic by Resistant Bacteria 107
Ch. 9 Antibiotic Resistance by Efflux Pumps 125
Ch. 10 Antibiotic Resistance by Replacement or Modification of the Antibiotic Target 143
Sect. IV Antibiotic Biosynthesis 157
Ch. 11 Regulation of Antibiotic Biosynthesis in Producer Organisms 159
Ch. 12 Polyketide Antibiotic Biosynthesis: Assembly-Line Enzymology 175
Ch. 13 Enzymatic Assembly Lines for Nonribosomal Peptide Antibiotics 195
Ch. 14 Biosynthesis of Other Classes of Antibiotics 221
Sect. V New Strategies for Finding Novel Antibiotics and Extending Their Lifetimes 235
Ch. 15 New Looks at Targets 237
Ch. 16 New Molecules 271
Ch. 17 Contexts and Challenges for the Use of New Antibiotics 285
References 297
Index 329
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)