Antimicrobial Peptides

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Describes the structure and function of important peptides from several different organisms. An exciting development is the use of these peptides or their analogues in the treatment and prevention of infectious diseases. Considers ways in which these peptides may be used to control the insect vectors of key pathogens including the malarial parasite. Discusses the role of antimicrobial peptides in the mammalian immune system and their interaction with other components of that ...
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1994 Hard cover New. No dust jacket as issued. Sewn binding. Cloth over boards. 292 p. CIBA Foundation Symposia, 186. Audience: General/trade. Brand New-Never Used Hardcover-No ... Marks or Highlights-Ships with Tracking # Read more Show Less

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Overview

Describes the structure and function of important peptides from several different organisms. An exciting development is the use of these peptides or their analogues in the treatment and prevention of infectious diseases. Considers ways in which these peptides may be used to control the insect vectors of key pathogens including the malarial parasite. Discusses the role of antimicrobial peptides in the mammalian immune system and their interaction with other components of that system.

Function of antimicrobial proteins in insects/antimicrobial peptides from bees/etc.

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Product Details

  • ISBN-13: 9780471950257
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 11/28/1994
  • Series: Novartis Foundation Symposia Series , #111
  • Edition number: 1
  • Pages: 292
  • Product dimensions: 6.40 (w) x 9.43 (h) x 0.88 (d)

Table of Contents

Chairman's opening remarks 1
Design and synthesis of antimicrobial peptides 5
Gene-encoded antibiotics made in bacteria 27
General discussion I: Assaying antimicrobial activity 54
Biosynthesis of defensins and other antimicrobial peptides 62
Antimicrobial peptides from amphibian skin: an overview 77
Gene-encoded antimicrobial peptides from plants 91
Drosophila as a model system for antibacterial peptides 107
Function of antimicrobial proteins in insects 123
General discussion II: Antimicrobial peptides from bees 135
Antibacterial peptides in insect vectors of tropical parasitic disease 140
Structure-function relationships of tachyplesins and their analogues 160
Bactericidal permeability-increasing protein in host defence against Gram-negative bacteria and endotoxin 176
General discussion III
Mechanism of membrane permeation by cecropin B2 190
Potential therapeutic applications of magainins and other antimicrobial agents of animal origin 197
Primitive vertebrate immunity: what is the evolutionary derivation of molecules that define the adaptive immune system? 224
Antimicrobial proteins with homology to serine proteases 237
Antimicrobial peptides as agents of mucosal immunity 250
Closing remarks 270
Index of contributors 273
Subject index 275
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