Antithrombotic Drug Therapy in Cardiovascular Disease / Edition 1

Antithrombotic Drug Therapy in Cardiovascular Disease / Edition 1

by Arman T. Askari, A Michael Lincoff
     
 

ISBN-10: 1603272348

ISBN-13: 9781603272346

Pub. Date: 11/28/2009

Publisher: Springer-Verlag New York, LLC

Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis plays an essential role in the pathogenesis of acute coronary syndromes (ACS), ischemic complications of percutaneous coronary intervention (PCI), venous thromboembolic

Overview

Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis plays an essential role in the pathogenesis of acute coronary syndromes (ACS), ischemic complications of percutaneous coronary intervention (PCI), venous thromboembolic disease, and embolic complications of arrhythmias and various cardiomyopathies.

Written by experts in the field, Antithrombotic Drug Therapy in Cardiovascular Disease carefully examines individual and various combinations of the available antithrombotic regimens including fibrinolytic agents, antiplatelet therapies (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticoagulant therapies (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and synthetic factor X inhibitors), non-ST-segment elevation (NSTE) ACS and ST-segment elevation myocardial infarction (STEMI). A detailed overview, Antithrombotic Drug Therapy in Cardiovascular Disease presents the evidence demonstrating the efficacy of available antithrombotic therapies in specific disease states such as atrial fibrillation, cardiomyopathy, valvular heart disease, and heparin-induced thrombocytopenia (HIT).

Product Details

ISBN-13:
9781603272346
Publisher:
Springer-Verlag New York, LLC
Publication date:
11/28/2009
Series:
Contemporary Cardiology Series
Edition description:
2010
Pages:
475
Product dimensions:
7.70(w) x 10.40(h) x 1.40(d)

Table of Contents

Part 1: Basic Principles

Chapter 1 The Platelet in Arterial and Venous Thrombosis
Peter Kelly, MD
Edward F. Plow, PhD

Chapter 2 The Coagulation Cascade in Arterial and Venous Thrombosis
Kandice Marchant, MD, PhD

Chapter 3 The Link Between Thrombosis and Inflammation
John H. Cleator, MD
Mark Robbins, MD

Chapter 4 Genetics of Thrombosis
Svati H. Shah, MD, MHS
Richard C. Becker, MD

Part II: Antithrombotic Therapy for Stable Coronary Atherosclerotic Disease

Chapter 5 Aspirin for Primary and Secondary Prevention
Jinesh Kochar, MD, MPH
J, Michael Gaziano, MD, MPH

Chapter 6 Thienopyridines in Stable CAD Patients
Dipak Kotecha, MBChB., MRCP.
Marcus D. Flather, MBBS, FRCP

Part III: Antithrombotic Therapy for NSTE ACS

Chapter 7 Anti-platelet Therapies: Aspirin, Thienopyridines, and Glycoprotein IIb/IIIa Inhibitors
Saif Anwaruddin MD
Deepak L. Bhatt MD

Chapter 8 Unfractionated Heparin and Enoxaparin
Pierluigi Tricoci, MD, MHS, PhD
Kenneth W. Mahaffey, MD

Chapter 9 The Direct Thrombin Ihibitors
Tyler Taigen, MD
James Harvey, MD
A. Michael Lincoff, MD

Chapter 10 Synthetic Factor Xa Inhibition, Fondaparinux
Michael S. Kim, MD
Robert L. Page, Pharm.D
Ivan P. Casserly, MBBCh

Part IV: Antithrombotic Therapy for STEMI

Chapter 11 Antiplatelet Therapies: Aspirin,Clopidogrel and thienopyridines and Glycoprotien IIb/IIIa Inhibitors
Rory B. Weiner, MD
Marc S. Sabatine, MD, MPH

Chapter 12 Antithrombin Therapies: Unfractionated Heparin, Enoxaparin, Direct Thrombin Inhibitors, Fondaparinux
John M. Galla, MD
Arman T. Askari, MD

Chapter 13 Fibrinolysis and Facilitated PCI
RyanD. Christofferson, MD
Sorin J. Brener, MD

Part V: Antithrombotic Therapy in Interventional Cardiology

Chapter 14 Antithrombotic Therapy in Percutaneous Coronary Intervention
Adrian W. Messerli, MD

Chapter 15 Antithrombotic Therapy in Carotid and Peripheral Intervention
Thomas J. Helton, MD
Samir R. Kapadia, MD

Chapter 16 Monitoring of Antithrombotic Therapies
Kristofer Dosh, MD
Steven Steinhubl, MD

Part VI: Antithrombotic Therapy in Venous Thromboembolic Disease

Chapter 17 Antithrombotic Therapy for DVT/PE
Esther S.H. Kim, MD
John R. Bartholomew, MD

Chapter 18 Fibrinolysis for PE
Stavros V. Konstantinides, MD

Chapter 19 Duration of Anticoagulation Following VTE
Clive Kearon, MB MRCPI FRCPC PhD

Part VII: Clinical Considerations

Chapter 20 Antithrombotic Therapy for Atrial Fibrillation
Carmel M. Halley MD
Allan L. Klein MD

Chapter 21 Antithrombotic Therapy for Valvular Heart Disease
Noah Rosenthal MD
Brian D. Hoit MD

Chapter 22 Antithrombotic Therapy for Cardiomyopathy
Zuheir Abrahams MD PhD
George Sokos MD
W. H. Wilson Tang MD

Chapter 23 Heparin-Induced Thrombocytopenia
John R. Bartholomew, MD

Chapter 24 'Resistance' to Antiplatelet Therapies
Gerald C. Koenig, MD, PhD
Hitinder S. Gurm, MD

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