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The Art, Science, and Technology of Pharmaceutical Compounding / Edition 4
     

The Art, Science, and Technology of Pharmaceutical Compounding / Edition 4

by Loyd V. Allen, American Pharmacists Association Staff
 

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ISBN-10: 1582121648

ISBN-13: 9781582121642

Pub. Date: 07/28/2012

Publisher: APhA Publications

The new 4th edtion of The Art, Science, and Technology of Pharmaceutical Compounding presents in a logical and progressive format all the information that pharmacists and student pharmacists need to understand the purpose and processes of compounding. Author Loyd V. Allen Jr., the preeminent expert, covers basic guidelines, economic and technical factors that

Overview

The new 4th edtion of The Art, Science, and Technology of Pharmaceutical Compounding presents in a logical and progressive format all the information that pharmacists and student pharmacists need to understand the purpose and processes of compounding. Author Loyd V. Allen Jr., the preeminent expert, covers basic guidelines, economic and technical factors that compounding pharmacists must consider, and all aspects of good manufacturing practices for compounded medications. Key Features:
• The initial chapters describe the requisite facilities and equipment, record keeping, calculations, and quality control.
• A new chapter emphasizes the importance of knowing the purity and form of all ingredients to ensure that the proper dose of a compounded product is delivered.
• Fourteen chapters are devoted to the compounding of each dosage form in turn, from powders and granules to injectables.
• Additional chapters cover veterinary compounding, compounding for special populations, compounding for specific procedures, compounding for clinical studies, compounding cosmetics, compounding with hazardous drugs, and compounding in the event of a natural disaster or terrorist attack.
• Nine appendices provide essential information on the compounding process and examples of standard operating procedures.
• The necessary ingredients and steps are listed for compounding more than 200 sample formulations, including bases, vehicles, and ingredient-specific preparations.
• Updated throughout.

Product Details

ISBN-13:
9781582121642
Publisher:
APhA Publications
Publication date:
07/28/2012
Series:
4 , #4
Pages:
594
Sales rank:
617,023
Product dimensions:
6.80(w) x 10.10(h) x 1.20(d)

Table of Contents

Sample Formulationsvii
Preface to Second Editionxiii
Preface to First Editionxv
Introductionxix
Abbreviations and Approximate Solubility Descriptorsxxv
Chapter 1Guidelines for Compounding Practices1
Chapter 2Facilities, Equipment, and Supplies17
Chapter 3Records and Record Keeping33
Chapter 4Stability of Compounded Products43
Chapter 5Pharmaceutical Compounding Calculations53
Chapter 6Quality Control77
Chapter 7Flavors, Sweeteners, and Colors93
Chapter 8Preservation, Sterilization, and Depyrogenation105
Chapter 9Powders and Granules117
Chapter 10Capsules133
Chapter 11Tablets161
Chapter 12Lozenges/Troches171
Chapter 13Suppositories189
Chapter 14Sticks213
Chapter 15Solutions231
Chapter 16Suspensions249
Chapter 17Emulsions263
Chapter 18Ointments, Creams, and Pastes277
Chapter 19Gels301
Chapter 20Ophthalmic, Otic, and Nasal Preparations325
Chapter 21Inhalation Products353
Chapter 22Parenteral Preparations365
Chapter 23Biotechnology Preparations393
Chapter 24Compounding for Special Populations and Special Products401
Chapter 25Veterinary Pharmaceutical Compounding415
Appendix IAgents Withdrawn by FDA Because of Safety/Efficacy Concerns445
Appendix IISpecific Gravity Values455
Appendix IIISodium Chloride Equivalent Values of Selected Agents457
Appendix IVBuffers and Buffer Solutions467
Appendix VViscosity-Increasing Agents for Aqueous Systems473
Index477

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