Assisted Reproductive Technology: Accomplishments and New Horizons

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This insightful and thought-provoking collection of chapters describes the rapid advances that have revolutionized reproductive medicine. From oogenesis and spermatogenesis, through to fertilization, embryogenesis, and cloning, this volume looks at cutting-edge technologies and scientific advances. Subsequent chapters focus on infertility and its diagnosis and treatment using the full armory of assisted reproductive technologies. A concluding section surveys the impact of these developments on the provision, regulation, and financing of reproductive health care in the global community.

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Editorial Reviews

From The Critics
Contributors from assorted medical and biological disciplines provide a snapshot of the field as it develops. Within sections on the gametes, techniques, the clinic, and concepts for the global community, they discuss such topics as attributes of fertile spermatozoa, influences of culture media on embryo development, embryonic stem cells, the diagnosis and treatment of male infertility and female subfertility, the natural and stimulated cycles, developing immuno-contraceptives, and legal and ethical aspects of cryopreservation of gametes and embryos. Annotation c. Book News, Inc., Portland, OR
From the Publisher
" authoritative account of current knowledge in the field of human reproductive biology and assisted conception." The Obstetrician & Gynaecologist

"...this text is suited to physicians and researchers...and may also be of interest to persons affected by or interested in infertility." Canadian Journal of Medical Laboratory Science

"The editors have done an excellent job of producing a topical and authoritative work that is simultaneously a joy to read." Journal of Andrology

"This book will appeal to practioners in reproductive medicine: scientists, clinicians and researchers." Bulletin of Science Technology and Society

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Product Details

  • ISBN-13: 9780521188951
  • Publisher: Cambridge University Press
  • Publication date: 3/3/2011
  • Edition description: Reissue
  • Pages: 450
  • Product dimensions: 7.50 (w) x 9.70 (h) x 1.00 (d)

Meet the Author

Professor Christopher De Jonge is Director of Laboratories at the Reproductive Medicine Center Department of Obstetrics and Gynecology, University of Minnesota.

Professor Christopher Barratt is Scientific Director at the Assisted Conception Unit, Birmingham Women's Hospital.

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Table of Contents

List of contributors
Pt. I The gametes: present and future
1 Spermatogenesis in vitro in mammals 3
2 The spermatozoon as a machine: compartmentalized pathways bridge cellular structure and function 26
3 Attributes of fertile spermatozoa 40
4 In vitro oogenesis 61
5 The oocyte as a machine 70
6 Follicular influences on oocyte and embryo competence 81
7 Unresolved and basic problems in assisted reproductive technology 106
Pt. II Techniques: present and future
8 Influences of culture media on embryo development 127
9 Cryopreservation of immature and mature gametes 144
10 Embryonic stem cells 167
11 Modification of the male genome by gene and spermatogonial transplantation 178
12 Genetic diagnosis: the future 186
13 Cloning mammals 206
14 Fluorescence imaging: gamete selection and intracellular sperm injection 217
Pt. III The clinic
15 Diagnosis and treatment of male infertility 231
16 Tests of male fertility 255
17 Diagnosis and treatment for female subfertility 272
18 Ultrasound imaging at the beginning of the second millennium 282
19 The natural and the stimulated cycle 302
20 Embryo stage and transfer number 311
21 The federal research base in the USA for assisted reproductive technology 320
Pt. IV Concepts for the global community
22 From conception to contraception 329
23 Developing immunocontraceptives 355
24 ARTistic license: should assisted reproductive technologies be regulated? 366
25 Finances and access to assisted reproductive technologies: justice and publication of results 376
26 Sex selection 384
27 Intracytoplasmic sperm injection: a time bomb? 397
28 Cryopreservation of gametes and embryos: legal and ethical aspects 407
Index 415
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